Anti-DNAJC10 monoclonal antibody

Pre-made anti-DNAJC10 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DNAJC10/DNAJC10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0704-Ab-1/ GM-Tg-hg-IP0704-Ab-2Anti-Human DNAJC10 monoclonal antibodyHuman
GM-Tg-rg-IP0704-Ab-1/ GM-Tg-rg-IP0704-Ab-2Anti-Rat DNAJC10 monoclonal antibodyRat
GM-Tg-mg-IP0704-Ab-1/ GM-Tg-mg-IP0704-Ab-2Anti-Mouse DNAJC10 monoclonal antibodyMouse
GM-Tg-cynog-IP0704-Ab-1/ GM-Tg-cynog-IP0704-Ab-2Anti-Cynomolgus/ Rhesus macaque DNAJC10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0704-Ab-1/ GM-Tg-felg-IP0704-Ab-2Anti-Feline DNAJC10 monoclonal antibodyFeline
GM-Tg-cang-IP0704-Ab-1/ GM-Tg-cang-IP0704-Ab-2Anti-Canine DNAJC10 monoclonal antibodyCanine
GM-Tg-bovg-IP0704-Ab-1/ GM-Tg-bovg-IP0704-Ab-2Anti-Bovine DNAJC10 monoclonal antibodyBovine
GM-Tg-equg-IP0704-Ab-1/ GM-Tg-equg-IP0704-Ab-2Anti-Equine DNAJC10 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0704-Ab-1/ GM-Tg-hg-IP0704-Ab-2; GM-Tg-rg-IP0704-Ab-1/ GM-Tg-rg-IP0704-Ab-2;
GM-Tg-mg-IP0704-Ab-1/ GM-Tg-mg-IP0704-Ab-2; GM-Tg-cynog-IP0704-Ab-1/ GM-Tg-cynog-IP0704-Ab-2;
GM-Tg-felg-IP0704-Ab-1/ GM-Tg-felg-IP0704-Ab-2; GM-Tg-cang-IP0704-Ab-1/ GM-Tg-cang-IP0704-Ab-2;
GM-Tg-bovg-IP0704-Ab-1/ GM-Tg-bovg-IP0704-Ab-2; GM-Tg-equg-IP0704-Ab-1/ GM-Tg-equg-IP0704-Ab-2
Products NameAnti-DNAJC10 monoclonal antibody
Formatmab
Target NameDNAJC10
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DNAJC10 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0704-Ag-1Recombinant multi-species DJC10/ DNAJC10/ ERdj5 protein
    ORF Viral VectorpGMLPm004740mouse Dnajc10 Lentivirus plasmid
    ORF Viral VectorvGMLPm004740mouse Dnajc10 Lentivirus particle


    Target information

    Target IDGM-IP0704
    Target NameDNAJC10
    Gene ID54431,66861,295690,705787,478826,101083533,613403,102147457
    Gene Symbol and Synonyms1200006L06Rik,D2Ertd706e,DNAJC10,ERdj5,JPDI,MTHr,PDIA19
    Uniprot AccessionQ8IXB1,Q498R3
    Uniprot Entry NameDJC10_HUMAN,DJC10_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000077232
    Target ClassificationN/A

    The target: DNAJC10, gene name: DNAJC10, also named as ERdj5, JPDI, MTHr, PDIA19. This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.