Anti-EVI5L monoclonal antibody

Pre-made anti-EVI5L monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to EVI5L/EVI5L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0781-Ab-1/ GM-Tg-hg-IP0781-Ab-2Anti-Human EVI5L monoclonal antibodyHuman
GM-Tg-rg-IP0781-Ab-1/ GM-Tg-rg-IP0781-Ab-2Anti-Rat EVI5L monoclonal antibodyRat
GM-Tg-mg-IP0781-Ab-1/ GM-Tg-mg-IP0781-Ab-2Anti-Mouse EVI5L monoclonal antibodyMouse
GM-Tg-cynog-IP0781-Ab-1/ GM-Tg-cynog-IP0781-Ab-2Anti-Cynomolgus/ Rhesus macaque EVI5L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0781-Ab-1/ GM-Tg-felg-IP0781-Ab-2Anti-Feline EVI5L monoclonal antibodyFeline
GM-Tg-cang-IP0781-Ab-1/ GM-Tg-cang-IP0781-Ab-2Anti-Canine EVI5L monoclonal antibodyCanine
GM-Tg-bovg-IP0781-Ab-1/ GM-Tg-bovg-IP0781-Ab-2Anti-Bovine EVI5L monoclonal antibodyBovine
GM-Tg-equg-IP0781-Ab-1/ GM-Tg-equg-IP0781-Ab-2Anti-Equine EVI5L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0781-Ab-1/ GM-Tg-hg-IP0781-Ab-2; GM-Tg-rg-IP0781-Ab-1/ GM-Tg-rg-IP0781-Ab-2;
GM-Tg-mg-IP0781-Ab-1/ GM-Tg-mg-IP0781-Ab-2; GM-Tg-cynog-IP0781-Ab-1/ GM-Tg-cynog-IP0781-Ab-2;
GM-Tg-felg-IP0781-Ab-1/ GM-Tg-felg-IP0781-Ab-2; GM-Tg-cang-IP0781-Ab-1/ GM-Tg-cang-IP0781-Ab-2;
GM-Tg-bovg-IP0781-Ab-1/ GM-Tg-bovg-IP0781-Ab-2; GM-Tg-equg-IP0781-Ab-1/ GM-Tg-equg-IP0781-Ab-2
Products NameAnti-EVI5L monoclonal antibody
Formatmab
Target NameEVI5L
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-EVI5L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0781-Ag-1Recombinant multi-species EVI5L protein


    Target information

    Target IDGM-IP0781
    Target NameEVI5L
    Gene ID115704,213027,304201,706628,485001,101100948,536625,100147518
    Gene Symbol and Synonyms1700084G18Rik,2310039H16Rik,3110007G05Rik,B130050I23Rik,EVI5L,RGD1561962
    Uniprot AccessionQ96CN4
    Uniprot Entry NameEVI5L_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000142459
    Target ClassificationN/A

    The target: EVI5L, gene name: EVI5L, also named as . Enables GTPase activator activity and small GTPase binding activity. Involved in negative regulation of cilium assembly and positive regulation of GTPase activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.