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Anti-FADS1 monoclonal antibody
Pre-made anti-FADS1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FADS1/FADS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0787-Ab-1/ GM-Tg-hg-IP0787-Ab-2 | Anti-Human FADS1 monoclonal antibody | Human |
| GM-Tg-rg-IP0787-Ab-1/ GM-Tg-rg-IP0787-Ab-2 | Anti-Rat FADS1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0787-Ab-1/ GM-Tg-mg-IP0787-Ab-2 | Anti-Mouse FADS1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0787-Ab-1/ GM-Tg-cynog-IP0787-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FADS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0787-Ab-1/ GM-Tg-felg-IP0787-Ab-2 | Anti-Feline FADS1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0787-Ab-1/ GM-Tg-cang-IP0787-Ab-2 | Anti-Canine FADS1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0787-Ab-1/ GM-Tg-bovg-IP0787-Ab-2 | Anti-Bovine FADS1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0787-Ab-1/ GM-Tg-equg-IP0787-Ab-2 | Anti-Equine FADS1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0787-Ab-1/ GM-Tg-hg-IP0787-Ab-2; GM-Tg-rg-IP0787-Ab-1/ GM-Tg-rg-IP0787-Ab-2; GM-Tg-mg-IP0787-Ab-1/ GM-Tg-mg-IP0787-Ab-2; GM-Tg-cynog-IP0787-Ab-1/ GM-Tg-cynog-IP0787-Ab-2; GM-Tg-felg-IP0787-Ab-1/ GM-Tg-felg-IP0787-Ab-2; GM-Tg-cang-IP0787-Ab-1/ GM-Tg-cang-IP0787-Ab-2; GM-Tg-bovg-IP0787-Ab-1/ GM-Tg-bovg-IP0787-Ab-2; GM-Tg-equg-IP0787-Ab-1/ GM-Tg-equg-IP0787-Ab-2 |
| Products Name | Anti-FADS1 monoclonal antibody |
| Format | mab |
| Target Name | FADS1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FADS1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0787-Ag-1 | Recombinant multi-species FADS1/ D5D/ FADS6 protein |
| ORF Viral Vector | pGMLPm001527 | mouse Fads1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001527 | mouse Fads1 Lentivirus particle |
Target information
| Target ID | GM-IP0787 |
| Target Name | FADS1 |
| Gene ID | 3992,76267,84575,722343,483793,101083966,533107,102150261 |
| Gene Symbol and Synonyms | 0710001O03Rik,A930006B21Rik,D5D,DSD,FADS1,FADS6,FADSD5,LLCDL1,TU12 |
| Uniprot Accession | O60427,Q920R3 |
| Uniprot Entry Name | FADS1_HUMAN,FADS1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000149485 |
| Target Classification | N/A |
The target: FADS1, gene name: FADS1, also named as D5D, FADS6, FADSD5, LLCDL1, TU12. The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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