Anti-FAM173B monoclonal antibody

Pre-made anti-FAM173B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FAM173B/FAM173B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0806-Ab-1/ GM-Tg-hg-IP0806-Ab-2Anti-Human FAM173B monoclonal antibodyHuman
GM-Tg-rg-IP0806-Ab-1/ GM-Tg-rg-IP0806-Ab-2Anti-Rat FAM173B monoclonal antibodyRat
GM-Tg-mg-IP0806-Ab-1/ GM-Tg-mg-IP0806-Ab-2Anti-Mouse FAM173B monoclonal antibodyMouse
GM-Tg-cynog-IP0806-Ab-1/ GM-Tg-cynog-IP0806-Ab-2Anti-Cynomolgus/ Rhesus macaque FAM173B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0806-Ab-1/ GM-Tg-felg-IP0806-Ab-2Anti-Feline FAM173B monoclonal antibodyFeline
GM-Tg-cang-IP0806-Ab-1/ GM-Tg-cang-IP0806-Ab-2Anti-Canine FAM173B monoclonal antibodyCanine
GM-Tg-bovg-IP0806-Ab-1/ GM-Tg-bovg-IP0806-Ab-2Anti-Bovine FAM173B monoclonal antibodyBovine
GM-Tg-equg-IP0806-Ab-1/ GM-Tg-equg-IP0806-Ab-2Anti-Equine FAM173B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0806-Ab-1/ GM-Tg-hg-IP0806-Ab-2; GM-Tg-rg-IP0806-Ab-1/ GM-Tg-rg-IP0806-Ab-2;
GM-Tg-mg-IP0806-Ab-1/ GM-Tg-mg-IP0806-Ab-2; GM-Tg-cynog-IP0806-Ab-1/ GM-Tg-cynog-IP0806-Ab-2;
GM-Tg-felg-IP0806-Ab-1/ GM-Tg-felg-IP0806-Ab-2; GM-Tg-cang-IP0806-Ab-1/ GM-Tg-cang-IP0806-Ab-2;
GM-Tg-bovg-IP0806-Ab-1/ GM-Tg-bovg-IP0806-Ab-2; GM-Tg-equg-IP0806-Ab-1/ GM-Tg-equg-IP0806-Ab-2
Products NameAnti-FAM173B monoclonal antibody
Formatmab
Target NameFAM173B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FAM173B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0806-Ag-1Recombinant multi-species ACKMT/ FAM173B/ JS-2 protein


    Target information

    Target IDGM-IP0806
    Target NameFAM173B
    Gene ID134145,68073,499561,696383,478620,101097622,525138,100070925
    Gene Symbol and SynonymsA930016P21Rik,ATPSCKMT,FAM173B,hFAM173B,JS-2,mFam173b,RGD1560629
    Uniprot AccessionQ6P4H8,D3ZLY0
    Uniprot Entry NameACKMT_HUMAN,ACKMT_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000150756
    Target ClassificationN/A

    The target: FAM173B, gene name: FAM173B, also named as JS-2, hFAM173B. Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation; positive regulation of sensory perception of pain; and regulation of proton transport. Located in mitochondrial crista. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.