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Anti-FAR1 monoclonal antibody
Pre-made anti-FAR1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FAR1/FAR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0832-Ab-1/ GM-Tg-hg-IP0832-Ab-2 | Anti-Human FAR1 monoclonal antibody | Human |
| GM-Tg-rg-IP0832-Ab-1/ GM-Tg-rg-IP0832-Ab-2 | Anti-Rat FAR1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0832-Ab-1/ GM-Tg-mg-IP0832-Ab-2 | Anti-Mouse FAR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0832-Ab-1/ GM-Tg-cynog-IP0832-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FAR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0832-Ab-1/ GM-Tg-felg-IP0832-Ab-2 | Anti-Feline FAR1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0832-Ab-1/ GM-Tg-cang-IP0832-Ab-2 | Anti-Canine FAR1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0832-Ab-1/ GM-Tg-bovg-IP0832-Ab-2 | Anti-Bovine FAR1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0832-Ab-1/ GM-Tg-equg-IP0832-Ab-2 | Anti-Equine FAR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0832-Ab-1/ GM-Tg-hg-IP0832-Ab-2; GM-Tg-rg-IP0832-Ab-1/ GM-Tg-rg-IP0832-Ab-2; GM-Tg-mg-IP0832-Ab-1/ GM-Tg-mg-IP0832-Ab-2; GM-Tg-cynog-IP0832-Ab-1/ GM-Tg-cynog-IP0832-Ab-2; GM-Tg-felg-IP0832-Ab-1/ GM-Tg-felg-IP0832-Ab-2; GM-Tg-cang-IP0832-Ab-1/ GM-Tg-cang-IP0832-Ab-2; GM-Tg-bovg-IP0832-Ab-1/ GM-Tg-bovg-IP0832-Ab-2; GM-Tg-equg-IP0832-Ab-1/ GM-Tg-equg-IP0832-Ab-2 |
| Products Name | Anti-FAR1 monoclonal antibody |
| Format | mab |
| Target Name | FAR1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FAR1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0832-Ag-1 | Recombinant multi-species FACR1/ FAR1/ MLSTD2 protein |
Target information
| Target ID | GM-IP0832 |
| Target Name | FAR1 |
| Gene ID | 84188,67420,293173,699947,476863,101093138,525262,100071555 |
| Gene Symbol and Synonyms | 2600011M19Rik,2900034E22Rik,3732409C05Rik,CSPSD,FAR1,MLSTD2,PFCRD,SDR10E1 |
| Uniprot Accession | Q8WVX9,Q66H50 |
| Uniprot Entry Name | FACR1_HUMAN,FACR1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000197601 |
| Target Classification | N/A |
The target: FAR1, gene name: FAR1, also named as MLSTD2, PFCRD, SDR10E1. The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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