Anti-FATE1 monoclonal antibody

Pre-made anti-FATE1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FATE1/FATE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0834-Ab-1/ GM-Tg-hg-IP0834-Ab-2Anti-Human FATE1 monoclonal antibodyHuman
GM-Tg-rg-IP0834-Ab-1/ GM-Tg-rg-IP0834-Ab-2Anti-Rat FATE1 monoclonal antibodyRat
GM-Tg-mg-IP0834-Ab-1/ GM-Tg-mg-IP0834-Ab-2Anti-Mouse FATE1 monoclonal antibodyMouse
GM-Tg-cynog-IP0834-Ab-1/ GM-Tg-cynog-IP0834-Ab-2Anti-Cynomolgus/ Rhesus macaque FATE1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0834-Ab-1/ GM-Tg-felg-IP0834-Ab-2Anti-Feline FATE1 monoclonal antibodyFeline
GM-Tg-cang-IP0834-Ab-1/ GM-Tg-cang-IP0834-Ab-2Anti-Canine FATE1 monoclonal antibodyCanine
GM-Tg-bovg-IP0834-Ab-1/ GM-Tg-bovg-IP0834-Ab-2Anti-Bovine FATE1 monoclonal antibodyBovine
GM-Tg-equg-IP0834-Ab-1/ GM-Tg-equg-IP0834-Ab-2Anti-Equine FATE1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0834-Ab-1/ GM-Tg-hg-IP0834-Ab-2; GM-Tg-rg-IP0834-Ab-1/ GM-Tg-rg-IP0834-Ab-2;
GM-Tg-mg-IP0834-Ab-1/ GM-Tg-mg-IP0834-Ab-2; GM-Tg-cynog-IP0834-Ab-1/ GM-Tg-cynog-IP0834-Ab-2;
GM-Tg-felg-IP0834-Ab-1/ GM-Tg-felg-IP0834-Ab-2; GM-Tg-cang-IP0834-Ab-1/ GM-Tg-cang-IP0834-Ab-2;
GM-Tg-bovg-IP0834-Ab-1/ GM-Tg-bovg-IP0834-Ab-2; GM-Tg-equg-IP0834-Ab-1/ GM-Tg-equg-IP0834-Ab-2
Products NameAnti-FATE1 monoclonal antibody
Formatmab
Target NameFATE1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FATE1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0834-Ag-1Recombinant multi-species FATE1/ CT43/ FATE protein


    Target information

    Target IDGM-IP0834
    Target NameFATE1
    Gene ID89885,704368,481076,101099191,281153,100629779
    Gene Symbol and SynonymsCT43,FATE,FATE1
    Uniprot AccessionQ969F0,Q95LA0
    Uniprot Entry NameFATE1_HUMAN,FATE1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000147378
    Target ClassificationN/A

    The target: FATE1, gene name: FATE1, also named as CT43, FATE. This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.