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Anti-FMO5 monoclonal antibody
Pre-made anti-FMO5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FMO5/FMO5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0856-Ab-1/ GM-Tg-hg-IP0856-Ab-2 | Anti-Human FMO5 monoclonal antibody | Human |
| GM-Tg-rg-IP0856-Ab-1/ GM-Tg-rg-IP0856-Ab-2 | Anti-Rat FMO5 monoclonal antibody | Rat |
| GM-Tg-mg-IP0856-Ab-1/ GM-Tg-mg-IP0856-Ab-2 | Anti-Mouse FMO5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0856-Ab-1/ GM-Tg-cynog-IP0856-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FMO5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0856-Ab-1/ GM-Tg-felg-IP0856-Ab-2 | Anti-Feline FMO5 monoclonal antibody | Feline |
| GM-Tg-cang-IP0856-Ab-1/ GM-Tg-cang-IP0856-Ab-2 | Anti-Canine FMO5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0856-Ab-1/ GM-Tg-bovg-IP0856-Ab-2 | Anti-Bovine FMO5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0856-Ab-1/ GM-Tg-equg-IP0856-Ab-2 | Anti-Equine FMO5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0856-Ab-1/ GM-Tg-hg-IP0856-Ab-2; GM-Tg-rg-IP0856-Ab-1/ GM-Tg-rg-IP0856-Ab-2; GM-Tg-mg-IP0856-Ab-1/ GM-Tg-mg-IP0856-Ab-2; GM-Tg-cynog-IP0856-Ab-1/ GM-Tg-cynog-IP0856-Ab-2; GM-Tg-felg-IP0856-Ab-1/ GM-Tg-felg-IP0856-Ab-2; GM-Tg-cang-IP0856-Ab-1/ GM-Tg-cang-IP0856-Ab-2; GM-Tg-bovg-IP0856-Ab-1/ GM-Tg-bovg-IP0856-Ab-2; GM-Tg-equg-IP0856-Ab-1/ GM-Tg-equg-IP0856-Ab-2 |
| Products Name | Anti-FMO5 monoclonal antibody |
| Format | mab |
| Target Name | FMO5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FMO5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0856-Ag-1 | Recombinant multi-species FMO5 protein |
| ORF Viral Vector | pGMLP001141 | human FMO5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001141 | human FMO5 Lentivirus particle |
| ORF Viral Vector | pGMLPm003414 | mouse Fmo5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003414 | mouse Fmo5 Lentivirus particle |
Target information
| Target ID | GM-IP0856 |
| Target Name | FMO5 |
| Gene ID | 2330,14263,246248,709691,475819,101092533,788719,100065455 |
| Gene Symbol and Synonyms | 5033418D19Rik,FMO5,hBVMO1 |
| Uniprot Accession | P49326,Q8K4C0 |
| Uniprot Entry Name | FMO5_HUMAN,FMO5_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000131781 |
| Target Classification | N/A |
The target: FMO5, gene name: FMO5, also named as . Metabolic N-oxidation of the diet-derived amino-trimethylamine (™A) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced ™A N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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