Anti-FUT9 monoclonal antibody
Pre-made anti-FUT9 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP0872-Ab-1/ GM-Tg-hg-IP0872-Ab-2 | Anti-Human FUT9 monoclonal antibody | Human |
GM-Tg-rg-IP0872-Ab-1/ GM-Tg-rg-IP0872-Ab-2 | Anti-Rat FUT9 monoclonal antibody | Rat |
GM-Tg-mg-IP0872-Ab-1/ GM-Tg-mg-IP0872-Ab-2 | Anti-Mouse FUT9 monoclonal antibody | Mouse |
GM-Tg-cynog-IP0872-Ab-1/ GM-Tg-cynog-IP0872-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FUT9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP0872-Ab-1/ GM-Tg-felg-IP0872-Ab-2 | Anti-Feline FUT9 monoclonal antibody | Feline |
GM-Tg-cang-IP0872-Ab-1/ GM-Tg-cang-IP0872-Ab-2 | Anti-Canine FUT9 monoclonal antibody | Canine |
GM-Tg-bovg-IP0872-Ab-1/ GM-Tg-bovg-IP0872-Ab-2 | Anti-Bovine FUT9 monoclonal antibody | Bovine |
GM-Tg-equg-IP0872-Ab-1/ GM-Tg-equg-IP0872-Ab-2 | Anti-Equine FUT9 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP0872-Ab-1/ GM-Tg-hg-IP0872-Ab-2; GM-Tg-rg-IP0872-Ab-1/ GM-Tg-rg-IP0872-Ab-2; GM-Tg-mg-IP0872-Ab-1/ GM-Tg-mg-IP0872-Ab-2; GM-Tg-cynog-IP0872-Ab-1/ GM-Tg-cynog-IP0872-Ab-2; GM-Tg-felg-IP0872-Ab-1/ GM-Tg-felg-IP0872-Ab-2; GM-Tg-cang-IP0872-Ab-1/ GM-Tg-cang-IP0872-Ab-2; GM-Tg-bovg-IP0872-Ab-1/ GM-Tg-bovg-IP0872-Ab-2; GM-Tg-equg-IP0872-Ab-1/ GM-Tg-equg-IP0872-Ab-2 |
Products Name | Anti-FUT9 monoclonal antibody |
Format | mab |
Target Name | FUT9 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-FUT9 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP0872-Ag-1 | Recombinant multi-species FUT9/ Fuc-TIX protein |
ORF Viral Vector | pGMLPm004773 | mouse Fut9 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004773 | mouse Fut9 Lentivirus particle |
Target information
Target ID | GM-IP0872 |
Target Name | FUT9 |
Gene ID | 10690,14348,84597,708361,449027,101080384,282853,100071396 |
Gene Symbol and Synonyms | Fuc-TIX,FUT9,mFuc-TIX,mFUT9 |
Uniprot Accession | Q9Y231,Q99JB3,Q659L1,Q8HZR2 |
Uniprot Entry Name | FUT9_HUMAN,FUT9_RAT,FUT9_CANLF,FUT9_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000172461 |
Target Classification | N/A |
The target: FUT9, gene name: FUT9, also named as Fuc-TIX. The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.