- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-FUZ monoclonal antibody
Pre-made anti-FUZ monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FUZ/FUZ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0873-Ab-1/ GM-Tg-hg-IP0873-Ab-2 | Anti-Human FUZ monoclonal antibody | Human |
| GM-Tg-rg-IP0873-Ab-1/ GM-Tg-rg-IP0873-Ab-2 | Anti-Rat FUZ monoclonal antibody | Rat |
| GM-Tg-mg-IP0873-Ab-1/ GM-Tg-mg-IP0873-Ab-2 | Anti-Mouse FUZ monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0873-Ab-1/ GM-Tg-cynog-IP0873-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FUZ monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0873-Ab-1/ GM-Tg-felg-IP0873-Ab-2 | Anti-Feline FUZ monoclonal antibody | Feline |
| GM-Tg-cang-IP0873-Ab-1/ GM-Tg-cang-IP0873-Ab-2 | Anti-Canine FUZ monoclonal antibody | Canine |
| GM-Tg-bovg-IP0873-Ab-1/ GM-Tg-bovg-IP0873-Ab-2 | Anti-Bovine FUZ monoclonal antibody | Bovine |
| GM-Tg-equg-IP0873-Ab-1/ GM-Tg-equg-IP0873-Ab-2 | Anti-Equine FUZ monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0873-Ab-1/ GM-Tg-hg-IP0873-Ab-2; GM-Tg-rg-IP0873-Ab-1/ GM-Tg-rg-IP0873-Ab-2; GM-Tg-mg-IP0873-Ab-1/ GM-Tg-mg-IP0873-Ab-2; GM-Tg-cynog-IP0873-Ab-1/ GM-Tg-cynog-IP0873-Ab-2; GM-Tg-felg-IP0873-Ab-1/ GM-Tg-felg-IP0873-Ab-2; GM-Tg-cang-IP0873-Ab-1/ GM-Tg-cang-IP0873-Ab-2; GM-Tg-bovg-IP0873-Ab-1/ GM-Tg-bovg-IP0873-Ab-2; GM-Tg-equg-IP0873-Ab-1/ GM-Tg-equg-IP0873-Ab-2 |
| Products Name | Anti-FUZ monoclonal antibody |
| Format | mab |
| Target Name | FUZ |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FUZ monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0873-Ag-1 | Recombinant multi-species FUZZY/ FUZ/ CPLANE3 protein |
Target information
| Target ID | GM-IP0873 |
| Target Name | FUZ |
| Gene ID | 80199,70300,308577,719442,476409,101094308,528818,100052158 |
| Gene Symbol and Synonyms | 2600013E07Rik,b2b1273Clo,CPLANE3,FUZ,FY,NTD,RGD1310608 |
| Uniprot Accession | Q9BT04,Q3B756 |
| Uniprot Entry Name | FUZZY_HUMAN,FUZZY_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000010361 |
| Target Classification | N/A |
The target: FUZ, gene name: FUZ, also named as CPLANE3, FY, NTD. This gene encodes a planar cell polarity protein that is involved in ciliogenesis and directional cell movement. Knockout studies in mice exhibit neural tube defects and defective cilia, and mutations in this gene are associated with neural tube defects in humans. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
