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Anti-GDAP1L1 monoclonal antibody
Pre-made anti-GDAP1L1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GDAP1L1/GDAP1L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0896-Ab-1/ GM-Tg-hg-IP0896-Ab-2 | Anti-Human GDAP1L1 monoclonal antibody | Human |
| GM-Tg-rg-IP0896-Ab-1/ GM-Tg-rg-IP0896-Ab-2 | Anti-Rat GDAP1L1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0896-Ab-1/ GM-Tg-mg-IP0896-Ab-2 | Anti-Mouse GDAP1L1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0896-Ab-1/ GM-Tg-cynog-IP0896-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GDAP1L1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0896-Ab-1/ GM-Tg-felg-IP0896-Ab-2 | Anti-Feline GDAP1L1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0896-Ab-1/ GM-Tg-cang-IP0896-Ab-2 | Anti-Canine GDAP1L1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0896-Ab-1/ GM-Tg-bovg-IP0896-Ab-2 | Anti-Bovine GDAP1L1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0896-Ab-1/ GM-Tg-equg-IP0896-Ab-2 | Anti-Equine GDAP1L1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0896-Ab-1/ GM-Tg-hg-IP0896-Ab-2; GM-Tg-rg-IP0896-Ab-1/ GM-Tg-rg-IP0896-Ab-2; GM-Tg-mg-IP0896-Ab-1/ GM-Tg-mg-IP0896-Ab-2; GM-Tg-cynog-IP0896-Ab-1/ GM-Tg-cynog-IP0896-Ab-2; GM-Tg-felg-IP0896-Ab-1/ GM-Tg-felg-IP0896-Ab-2; GM-Tg-cang-IP0896-Ab-1/ GM-Tg-cang-IP0896-Ab-2; GM-Tg-bovg-IP0896-Ab-1/ GM-Tg-bovg-IP0896-Ab-2; GM-Tg-equg-IP0896-Ab-1/ GM-Tg-equg-IP0896-Ab-2 |
| Products Name | Anti-GDAP1L1 monoclonal antibody |
| Format | mab |
| Target Name | GDAP1L1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GDAP1L1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0896-Ag-1 | Recombinant multi-species GD1L1/ GDAP1L1/ dJ881L22.1 protein |
Target information
| Target ID | GM-IP0896 |
| Target Name | GDAP1L1 |
| Gene ID | 78997,228858,311616,693773,485881,101093765,541158,100055926 |
| Gene Symbol and Synonyms | dJ881L22.1,dJ995J12.1.1,Gdap1l,GDAP1L1 |
| Uniprot Accession | Q96MZ0 |
| Uniprot Entry Name | GD1L1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000124194 |
| Target Classification | N/A |
The target: GDAP1L1, gene name: GDAP1L1, also named as dJ881L22.1, dJ995J12.1.1. The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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