Anti-GHI™ monoclonal antibody

Pre-made anti-GHI™ monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GHI™/GHI™ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0904-Ab-1/ GM-Tg-hg-IP0904-Ab-2Anti-Human GHI™ monoclonal antibodyHuman
GM-Tg-rg-IP0904-Ab-1/ GM-Tg-rg-IP0904-Ab-2Anti-Rat GHI™ monoclonal antibodyRat
GM-Tg-mg-IP0904-Ab-1/ GM-Tg-mg-IP0904-Ab-2Anti-Mouse GHI™ monoclonal antibodyMouse
GM-Tg-cynog-IP0904-Ab-1/ GM-Tg-cynog-IP0904-Ab-2Anti-Cynomolgus/ Rhesus macaque GHI™ monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0904-Ab-1/ GM-Tg-felg-IP0904-Ab-2Anti-Feline GHI™ monoclonal antibodyFeline
GM-Tg-cang-IP0904-Ab-1/ GM-Tg-cang-IP0904-Ab-2Anti-Canine GHI™ monoclonal antibodyCanine
GM-Tg-bovg-IP0904-Ab-1/ GM-Tg-bovg-IP0904-Ab-2Anti-Bovine GHI™ monoclonal antibodyBovine
GM-Tg-equg-IP0904-Ab-1/ GM-Tg-equg-IP0904-Ab-2Anti-Equine GHI™ monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0904-Ab-1/ GM-Tg-hg-IP0904-Ab-2; GM-Tg-rg-IP0904-Ab-1/ GM-Tg-rg-IP0904-Ab-2;
GM-Tg-mg-IP0904-Ab-1/ GM-Tg-mg-IP0904-Ab-2; GM-Tg-cynog-IP0904-Ab-1/ GM-Tg-cynog-IP0904-Ab-2;
GM-Tg-felg-IP0904-Ab-1/ GM-Tg-felg-IP0904-Ab-2; GM-Tg-cang-IP0904-Ab-1/ GM-Tg-cang-IP0904-Ab-2;
GM-Tg-bovg-IP0904-Ab-1/ GM-Tg-bovg-IP0904-Ab-2; GM-Tg-equg-IP0904-Ab-1/ GM-Tg-equg-IP0904-Ab-2
Products NameAnti-GHI™ monoclonal antibody
Formatmab
Target NameGHI™
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GHI™ monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0904-Ag-1Recombinant multi-species GHI™/ DERP2/ HSPC282 protein


    Target information

    Target IDGM-IP0904
    Target NameGHI™
    Gene ID27069,66092,290596,702691,479266,101082521,404143,100052687
    Gene Symbol and Synonyms1010001P14Rik,DERP2,GHI™,HSPC282,MICS1,My021,PTD010,™BIM5
    Uniprot AccessionQ9H3K2,Q5XIA8
    Uniprot Entry NameGHI™_HUMAN,GHI™_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165678
    Target ClassificationN/A

    The target: GHI™, gene name: GHI™, also named as DERP2, HSPC282, MICS1, My021, PTD010, ™BIM5. Involved in inner mitochondrial membrane organization and negative regulation of release of cytochrome c from mitochondria. Located in mitochondrion. Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.