Anti-GIMAP5 monoclonal antibody

Pre-made anti-GIMAP5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GIMAP5/GIMAP5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0908-Ab-1/ GM-Tg-hg-IP0908-Ab-2Anti-Human GIMAP5 monoclonal antibodyHuman
GM-Tg-rg-IP0908-Ab-1/ GM-Tg-rg-IP0908-Ab-2Anti-Rat GIMAP5 monoclonal antibodyRat
GM-Tg-mg-IP0908-Ab-1/ GM-Tg-mg-IP0908-Ab-2Anti-Mouse GIMAP5 monoclonal antibodyMouse
GM-Tg-cynog-IP0908-Ab-1/ GM-Tg-cynog-IP0908-Ab-2Anti-Cynomolgus/ Rhesus macaque GIMAP5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0908-Ab-1/ GM-Tg-felg-IP0908-Ab-2Anti-Feline GIMAP5 monoclonal antibodyFeline
GM-Tg-cang-IP0908-Ab-1/ GM-Tg-cang-IP0908-Ab-2Anti-Canine GIMAP5 monoclonal antibodyCanine
GM-Tg-bovg-IP0908-Ab-1/ GM-Tg-bovg-IP0908-Ab-2Anti-Bovine GIMAP5 monoclonal antibodyBovine
GM-Tg-equg-IP0908-Ab-1/ GM-Tg-equg-IP0908-Ab-2Anti-Equine GIMAP5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0908-Ab-1/ GM-Tg-hg-IP0908-Ab-2; GM-Tg-rg-IP0908-Ab-1/ GM-Tg-rg-IP0908-Ab-2;
GM-Tg-mg-IP0908-Ab-1/ GM-Tg-mg-IP0908-Ab-2; GM-Tg-cynog-IP0908-Ab-1/ GM-Tg-cynog-IP0908-Ab-2;
GM-Tg-felg-IP0908-Ab-1/ GM-Tg-felg-IP0908-Ab-2; GM-Tg-cang-IP0908-Ab-1/ GM-Tg-cang-IP0908-Ab-2;
GM-Tg-bovg-IP0908-Ab-1/ GM-Tg-bovg-IP0908-Ab-2; GM-Tg-equg-IP0908-Ab-1/ GM-Tg-equg-IP0908-Ab-2
Products NameAnti-GIMAP5 monoclonal antibody
Formatmab
Target NameGIMAP5
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GIMAP5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0908-Ag-1Recombinant multi-species GIMA5/ GIMAP5/ HIMAP3 protein
    ORF Viral VectorvGMLP000389human GIMAP5 Lentivirus particle
    ORF Viral VectorpGMLP000389human GIMAP5 Lentivirus plasmid
    ORF Viral VectorpGMLPm000544mouse Gimap5 Lentivirus plasmid
    ORF Viral VectorvGMLPm000544mouse Gimap5 Lentivirus particle


    Target information

    Target IDGM-IP0908
    Target NameGIMAP5
    Gene ID55340,713835,101081130
    Gene Symbol and SynonymsGIMAP1-GIMAP5,GIMAP5,HIMAP3,IAN-5,IAN4,IAN4L1,IAN5,IMAP3,IROD,NCPH2
    Uniprot AccessionQ96F15
    Uniprot Entry NameGIMA5_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196329
    Target ClassificationN/A

    The target: GIMAP5, gene name: GIMAP5, also named as HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD. This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.