Anti-GK2 monoclonal antibody

Pre-made anti-GK2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GK2/GK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0911-Ab-1/ GM-Tg-hg-IP0911-Ab-2Anti-Human GK2 monoclonal antibodyHuman
GM-Tg-rg-IP0911-Ab-1/ GM-Tg-rg-IP0911-Ab-2Anti-Rat GK2 monoclonal antibodyRat
GM-Tg-mg-IP0911-Ab-1/ GM-Tg-mg-IP0911-Ab-2Anti-Mouse GK2 monoclonal antibodyMouse
GM-Tg-cynog-IP0911-Ab-1/ GM-Tg-cynog-IP0911-Ab-2Anti-Cynomolgus/ Rhesus macaque GK2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0911-Ab-1/ GM-Tg-felg-IP0911-Ab-2Anti-Feline GK2 monoclonal antibodyFeline
GM-Tg-cang-IP0911-Ab-1/ GM-Tg-cang-IP0911-Ab-2Anti-Canine GK2 monoclonal antibodyCanine
GM-Tg-bovg-IP0911-Ab-1/ GM-Tg-bovg-IP0911-Ab-2Anti-Bovine GK2 monoclonal antibodyBovine
GM-Tg-equg-IP0911-Ab-1/ GM-Tg-equg-IP0911-Ab-2Anti-Equine GK2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0911-Ab-1/ GM-Tg-hg-IP0911-Ab-2; GM-Tg-rg-IP0911-Ab-1/ GM-Tg-rg-IP0911-Ab-2;
GM-Tg-mg-IP0911-Ab-1/ GM-Tg-mg-IP0911-Ab-2; GM-Tg-cynog-IP0911-Ab-1/ GM-Tg-cynog-IP0911-Ab-2;
GM-Tg-felg-IP0911-Ab-1/ GM-Tg-felg-IP0911-Ab-2; GM-Tg-cang-IP0911-Ab-1/ GM-Tg-cang-IP0911-Ab-2;
GM-Tg-bovg-IP0911-Ab-1/ GM-Tg-bovg-IP0911-Ab-2; GM-Tg-equg-IP0911-Ab-1/ GM-Tg-equg-IP0911-Ab-2
Products NameAnti-GK2 monoclonal antibody
Formatmab
Target NameGK2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GK2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0911-Ag-1Recombinant multi-species GLPK2/ GK2/ GKP2 protein


    Target information

    Target IDGM-IP0911
    Target NameGK2
    Gene ID2712,14626,289481,696635,478448,101092682,540143,100051712
    Gene Symbol and SynonymsGk-rs2,GK2,GKP2,GKTA
    Uniprot AccessionQ14410
    Uniprot Entry NameGLPK2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196475
    Target ClassificationN/A

    The target: GK2, gene name: GK2, also named as GKP2, GKTA. Predicted to enable glycerol kinase activity. Predicted to be involved in several processes, including glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.