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Anti-GOLGA5 monoclonal antibody
Pre-made anti-GOLGA5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GOLGA5/GOLGA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0918-Ab-1/ GM-Tg-hg-IP0918-Ab-2 | Anti-Human GOLGA5 monoclonal antibody | Human |
| GM-Tg-rg-IP0918-Ab-1/ GM-Tg-rg-IP0918-Ab-2 | Anti-Rat GOLGA5 monoclonal antibody | Rat |
| GM-Tg-mg-IP0918-Ab-1/ GM-Tg-mg-IP0918-Ab-2 | Anti-Mouse GOLGA5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0918-Ab-1/ GM-Tg-cynog-IP0918-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GOLGA5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0918-Ab-1/ GM-Tg-felg-IP0918-Ab-2 | Anti-Feline GOLGA5 monoclonal antibody | Feline |
| GM-Tg-cang-IP0918-Ab-1/ GM-Tg-cang-IP0918-Ab-2 | Anti-Canine GOLGA5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0918-Ab-1/ GM-Tg-bovg-IP0918-Ab-2 | Anti-Bovine GOLGA5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0918-Ab-1/ GM-Tg-equg-IP0918-Ab-2 | Anti-Equine GOLGA5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0918-Ab-1/ GM-Tg-hg-IP0918-Ab-2; GM-Tg-rg-IP0918-Ab-1/ GM-Tg-rg-IP0918-Ab-2; GM-Tg-mg-IP0918-Ab-1/ GM-Tg-mg-IP0918-Ab-2; GM-Tg-cynog-IP0918-Ab-1/ GM-Tg-cynog-IP0918-Ab-2; GM-Tg-felg-IP0918-Ab-1/ GM-Tg-felg-IP0918-Ab-2; GM-Tg-cang-IP0918-Ab-1/ GM-Tg-cang-IP0918-Ab-2; GM-Tg-bovg-IP0918-Ab-1/ GM-Tg-bovg-IP0918-Ab-2; GM-Tg-equg-IP0918-Ab-1/ GM-Tg-equg-IP0918-Ab-2 |
| Products Name | Anti-GOLGA5 monoclonal antibody |
| Format | mab |
| Target Name | GOLGA5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GOLGA5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0918-Ag-1 | Recombinant multi-species GOGA5/ GOLGA5/ GOLIM5 protein |
Target information
| Target ID | GM-IP0918 |
| Target Name | GOLGA5 |
| Gene ID | 9950,27277,299258,698378,480233,101098721,510412,111767491 |
| Gene Symbol and Synonyms | GOLGA5,GOLIM5,ret-II,RFG5 |
| Uniprot Accession | Q8TBA6,Q3ZU82 |
| Uniprot Entry Name | GOGA5_HUMAN,GOGA5_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000066455 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: GOLGA5, gene name: GOLGA5, also named as GOLIM5, RFG5, ret-II. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. A pseudogene of this gene is located on the short arm of chromosome 5. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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