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Anti-ADGRG4 monoclonal antibody
Pre-made anti-ADGRG4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ADGRG4/ADGRG4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0928-Ab-1/ GM-Tg-hg-IP0928-Ab-2 | Anti-Human ADGRG4 monoclonal antibody | Human |
| GM-Tg-rg-IP0928-Ab-1/ GM-Tg-rg-IP0928-Ab-2 | Anti-Rat ADGRG4 monoclonal antibody | Rat |
| GM-Tg-mg-IP0928-Ab-1/ GM-Tg-mg-IP0928-Ab-2 | Anti-Mouse ADGRG4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0928-Ab-1/ GM-Tg-cynog-IP0928-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ADGRG4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0928-Ab-1/ GM-Tg-felg-IP0928-Ab-2 | Anti-Feline ADGRG4 monoclonal antibody | Feline |
| GM-Tg-cang-IP0928-Ab-1/ GM-Tg-cang-IP0928-Ab-2 | Anti-Canine ADGRG4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0928-Ab-1/ GM-Tg-bovg-IP0928-Ab-2 | Anti-Bovine ADGRG4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0928-Ab-1/ GM-Tg-equg-IP0928-Ab-2 | Anti-Equine ADGRG4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0928-Ab-1/ GM-Tg-hg-IP0928-Ab-2; GM-Tg-rg-IP0928-Ab-1/ GM-Tg-rg-IP0928-Ab-2; GM-Tg-mg-IP0928-Ab-1/ GM-Tg-mg-IP0928-Ab-2; GM-Tg-cynog-IP0928-Ab-1/ GM-Tg-cynog-IP0928-Ab-2; GM-Tg-felg-IP0928-Ab-1/ GM-Tg-felg-IP0928-Ab-2; GM-Tg-cang-IP0928-Ab-1/ GM-Tg-cang-IP0928-Ab-2; GM-Tg-bovg-IP0928-Ab-1/ GM-Tg-bovg-IP0928-Ab-2; GM-Tg-equg-IP0928-Ab-1/ GM-Tg-equg-IP0928-Ab-2 |
| Products Name | Anti-ADGRG4 monoclonal antibody |
| Format | mab |
| Target Name | ADGRG4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ADGRG4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0928-Ag-1 | Recombinant multi-species AGRG4/ ADGRG4/ GPR112 protein |
Target information
| Target ID | GM-IP0928 |
| Target Name | ADGRG4 |
| Gene ID | 139378,236798,302860,100424734,492163,111558686,100056865 |
| Gene Symbol and Synonyms | ADGRG4,Gm367,GPR112,Gpr112l,PGR17,RGD1564057,RP1-299I16 |
| Uniprot Accession | Q8IZF6 |
| Uniprot Entry Name | AGRG4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000156920 |
| Target Classification | GPCR |
The target: ADGRG4, gene name: ADGRG4, also named as GPR112, PGR17, RP1-299I16. This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
