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Anti-GPR151 monoclonal antibody
Pre-made anti-GPR151 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GPR151/GPR151 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0935-Ab-1/ GM-Tg-hg-IP0935-Ab-2 | Anti-Human GPR151 monoclonal antibody | Human |
| GM-Tg-rg-IP0935-Ab-1/ GM-Tg-rg-IP0935-Ab-2 | Anti-Rat GPR151 monoclonal antibody | Rat |
| GM-Tg-mg-IP0935-Ab-1/ GM-Tg-mg-IP0935-Ab-2 | Anti-Mouse GPR151 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0935-Ab-1/ GM-Tg-cynog-IP0935-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GPR151 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0935-Ab-1/ GM-Tg-felg-IP0935-Ab-2 | Anti-Feline GPR151 monoclonal antibody | Feline |
| GM-Tg-cang-IP0935-Ab-1/ GM-Tg-cang-IP0935-Ab-2 | Anti-Canine GPR151 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0935-Ab-1/ GM-Tg-bovg-IP0935-Ab-2 | Anti-Bovine GPR151 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0935-Ab-1/ GM-Tg-equg-IP0935-Ab-2 | Anti-Equine GPR151 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0935-Ab-1/ GM-Tg-hg-IP0935-Ab-2; GM-Tg-rg-IP0935-Ab-1/ GM-Tg-rg-IP0935-Ab-2; GM-Tg-mg-IP0935-Ab-1/ GM-Tg-mg-IP0935-Ab-2; GM-Tg-cynog-IP0935-Ab-1/ GM-Tg-cynog-IP0935-Ab-2; GM-Tg-felg-IP0935-Ab-1/ GM-Tg-felg-IP0935-Ab-2; GM-Tg-cang-IP0935-Ab-1/ GM-Tg-cang-IP0935-Ab-2; GM-Tg-bovg-IP0935-Ab-1/ GM-Tg-bovg-IP0935-Ab-2; GM-Tg-equg-IP0935-Ab-1/ GM-Tg-equg-IP0935-Ab-2 |
| Products Name | Anti-GPR151 monoclonal antibody |
| Format | mab |
| Target Name | GPR151 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GPR151 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0935-Ag-1 | Recombinant multi-species GP151/ GPR151/ GALR4 protein |
Target information
| Target ID | GM-IP0935 |
| Target Name | GPR151 |
| Gene ID | 134391,240239,307475,708020,487201,101083825,787899,100060990 |
| Gene Symbol and Synonyms | C130082O03Rik,GALR4,GALRL,GPCR,GPCR-2037,GPR151,nGPCR-2037,PGR7 |
| Uniprot Accession | Q8TDV0,Q7TSN5 |
| Uniprot Entry Name | GP151_HUMAN,GP151_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000173250 |
| Target Classification | GPCR |
The target: GPR151, gene name: GPR151, also named as GALR4, GALRL, GPCR, GPCR-2037, PGR7. This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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