Anti-GTF3C1 monoclonal antibody

Pre-made anti-GTF3C1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GTF3C1/GTF3C1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0951-Ab-1/ GM-Tg-hg-IP0951-Ab-2Anti-Human GTF3C1 monoclonal antibodyHuman
GM-Tg-rg-IP0951-Ab-1/ GM-Tg-rg-IP0951-Ab-2Anti-Rat GTF3C1 monoclonal antibodyRat
GM-Tg-mg-IP0951-Ab-1/ GM-Tg-mg-IP0951-Ab-2Anti-Mouse GTF3C1 monoclonal antibodyMouse
GM-Tg-cynog-IP0951-Ab-1/ GM-Tg-cynog-IP0951-Ab-2Anti-Cynomolgus/ Rhesus macaque GTF3C1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0951-Ab-1/ GM-Tg-felg-IP0951-Ab-2Anti-Feline GTF3C1 monoclonal antibodyFeline
GM-Tg-cang-IP0951-Ab-1/ GM-Tg-cang-IP0951-Ab-2Anti-Canine GTF3C1 monoclonal antibodyCanine
GM-Tg-bovg-IP0951-Ab-1/ GM-Tg-bovg-IP0951-Ab-2Anti-Bovine GTF3C1 monoclonal antibodyBovine
GM-Tg-equg-IP0951-Ab-1/ GM-Tg-equg-IP0951-Ab-2Anti-Equine GTF3C1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0951-Ab-1/ GM-Tg-hg-IP0951-Ab-2; GM-Tg-rg-IP0951-Ab-1/ GM-Tg-rg-IP0951-Ab-2;
GM-Tg-mg-IP0951-Ab-1/ GM-Tg-mg-IP0951-Ab-2; GM-Tg-cynog-IP0951-Ab-1/ GM-Tg-cynog-IP0951-Ab-2;
GM-Tg-felg-IP0951-Ab-1/ GM-Tg-felg-IP0951-Ab-2; GM-Tg-cang-IP0951-Ab-1/ GM-Tg-cang-IP0951-Ab-2;
GM-Tg-bovg-IP0951-Ab-1/ GM-Tg-bovg-IP0951-Ab-2; GM-Tg-equg-IP0951-Ab-1/ GM-Tg-equg-IP0951-Ab-2
Products NameAnti-GTF3C1 monoclonal antibody
Formatmab
Target NameGTF3C1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GTF3C1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0951-Ag-1Recombinant multi-species TF3C1/ GTF3C1/ TFIIIC protein


    Target information

    Target IDGM-IP0951
    Target NameGTF3C1
    Gene ID2975,233863,171063,703998,489956,101086440,509874,100064518
    Gene Symbol and SynonymsGTF3C1,TF3C-alpha,TFIIIC,TFIIIC220,TFIIICalpha
    Uniprot AccessionQ12789,Q63505
    Uniprot Entry NameTF3C1_HUMAN,TF3C1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000077235
    Target ClassificationN/A

    The target: GTF3C1, gene name: GTF3C1, also named as TFIIIC, TFIIIC220, TFIIICalpha. Predicted to contribute to DNA binding activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and transcription initiation from RNA polymerase III promoter. Located in nucleolus and nucleoplasm. Part of transcription factor TFIIIC complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.