Anti-GTF3C3 monoclonal antibody

Pre-made anti-GTF3C3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to GTF3C3/GTF3C3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0952-Ab-1/ GM-Tg-hg-IP0952-Ab-2Anti-Human GTF3C3 monoclonal antibodyHuman
GM-Tg-rg-IP0952-Ab-1/ GM-Tg-rg-IP0952-Ab-2Anti-Rat GTF3C3 monoclonal antibodyRat
GM-Tg-mg-IP0952-Ab-1/ GM-Tg-mg-IP0952-Ab-2Anti-Mouse GTF3C3 monoclonal antibodyMouse
GM-Tg-cynog-IP0952-Ab-1/ GM-Tg-cynog-IP0952-Ab-2Anti-Cynomolgus/ Rhesus macaque GTF3C3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0952-Ab-1/ GM-Tg-felg-IP0952-Ab-2Anti-Feline GTF3C3 monoclonal antibodyFeline
GM-Tg-cang-IP0952-Ab-1/ GM-Tg-cang-IP0952-Ab-2Anti-Canine GTF3C3 monoclonal antibodyCanine
GM-Tg-bovg-IP0952-Ab-1/ GM-Tg-bovg-IP0952-Ab-2Anti-Bovine GTF3C3 monoclonal antibodyBovine
GM-Tg-equg-IP0952-Ab-1/ GM-Tg-equg-IP0952-Ab-2Anti-Equine GTF3C3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0952-Ab-1/ GM-Tg-hg-IP0952-Ab-2; GM-Tg-rg-IP0952-Ab-1/ GM-Tg-rg-IP0952-Ab-2;
GM-Tg-mg-IP0952-Ab-1/ GM-Tg-mg-IP0952-Ab-2; GM-Tg-cynog-IP0952-Ab-1/ GM-Tg-cynog-IP0952-Ab-2;
GM-Tg-felg-IP0952-Ab-1/ GM-Tg-felg-IP0952-Ab-2; GM-Tg-cang-IP0952-Ab-1/ GM-Tg-cang-IP0952-Ab-2;
GM-Tg-bovg-IP0952-Ab-1/ GM-Tg-bovg-IP0952-Ab-2; GM-Tg-equg-IP0952-Ab-1/ GM-Tg-equg-IP0952-Ab-2
Products NameAnti-GTF3C3 monoclonal antibody
Formatmab
Target NameGTF3C3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-GTF3C3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0952-Ag-1Recombinant multi-species TF3C3/ GTF3C3/ TFIIIC102 protein


    Target information

    Target IDGM-IP0952
    Target NameGTF3C3
    Gene ID9330,98488,316810,696338,478851,101087767,522473,100055057
    Gene Symbol and SynonymsGTF3C3,TF3C-gamma,TFIIIC102,TFiiiC2-102,TFIIICgamma
    Uniprot AccessionQ9Y5Q9
    Uniprot Entry NameTF3C3_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000119041
    Target ClassificationN/A

    The target: GTF3C3, gene name: GTF3C3, also named as TFIIIC102, TFIIICgamma, TFiiiC2-102. The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.