Anti-HEATR5A monoclonal antibody

Pre-made anti-HEATR5A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to HEATR5A/HEATR5A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0957-Ab-1/ GM-Tg-hg-IP0957-Ab-2Anti-Human HEATR5A monoclonal antibodyHuman
GM-Tg-rg-IP0957-Ab-1/ GM-Tg-rg-IP0957-Ab-2Anti-Rat HEATR5A monoclonal antibodyRat
GM-Tg-mg-IP0957-Ab-1/ GM-Tg-mg-IP0957-Ab-2Anti-Mouse HEATR5A monoclonal antibodyMouse
GM-Tg-cynog-IP0957-Ab-1/ GM-Tg-cynog-IP0957-Ab-2Anti-Cynomolgus/ Rhesus macaque HEATR5A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0957-Ab-1/ GM-Tg-felg-IP0957-Ab-2Anti-Feline HEATR5A monoclonal antibodyFeline
GM-Tg-cang-IP0957-Ab-1/ GM-Tg-cang-IP0957-Ab-2Anti-Canine HEATR5A monoclonal antibodyCanine
GM-Tg-bovg-IP0957-Ab-1/ GM-Tg-bovg-IP0957-Ab-2Anti-Bovine HEATR5A monoclonal antibodyBovine
GM-Tg-equg-IP0957-Ab-1/ GM-Tg-equg-IP0957-Ab-2Anti-Equine HEATR5A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0957-Ab-1/ GM-Tg-hg-IP0957-Ab-2; GM-Tg-rg-IP0957-Ab-1/ GM-Tg-rg-IP0957-Ab-2;
GM-Tg-mg-IP0957-Ab-1/ GM-Tg-mg-IP0957-Ab-2; GM-Tg-cynog-IP0957-Ab-1/ GM-Tg-cynog-IP0957-Ab-2;
GM-Tg-felg-IP0957-Ab-1/ GM-Tg-felg-IP0957-Ab-2; GM-Tg-cang-IP0957-Ab-1/ GM-Tg-cang-IP0957-Ab-2;
GM-Tg-bovg-IP0957-Ab-1/ GM-Tg-bovg-IP0957-Ab-2; GM-Tg-equg-IP0957-Ab-1/ GM-Tg-equg-IP0957-Ab-2
Products NameAnti-HEATR5A monoclonal antibody
Formatmab
Target NameHEATR5A
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-HEATR5A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0957-Ag-1Recombinant multi-species HTR5A/ HEATR5A/ C14orf125 protein


    Target information

    Target IDGM-IP0957
    Target NameHEATR5A
    Gene ID25938,320487,362737,716984,480285,101081812,507297,100050339
    Gene Symbol and SynonymsC14orf125,C230081H03Rik,D930036F22Rik,HEATR5A,mKIAA1316,p200b,RGD1561116
    Uniprot AccessionQ86XA9
    Uniprot Entry NameHTR5A_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000129493
    Target ClassificationN/A

    The target: HEATR5A, gene name: HEATR5A, also named as C14orf125. Predicted to be involved in endocytosis; protein localization; and retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be active in endocytic vesicle. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.