Anti-HRASLS2 monoclonal antibody

Pre-made anti-HRASLS2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to HRASLS2/HRASLS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0979-Ab-1/ GM-Tg-hg-IP0979-Ab-2Anti-Human HRASLS2 monoclonal antibodyHuman
GM-Tg-rg-IP0979-Ab-1/ GM-Tg-rg-IP0979-Ab-2Anti-Rat HRASLS2 monoclonal antibodyRat
GM-Tg-mg-IP0979-Ab-1/ GM-Tg-mg-IP0979-Ab-2Anti-Mouse HRASLS2 monoclonal antibodyMouse
GM-Tg-cynog-IP0979-Ab-1/ GM-Tg-cynog-IP0979-Ab-2Anti-Cynomolgus/ Rhesus macaque HRASLS2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0979-Ab-1/ GM-Tg-felg-IP0979-Ab-2Anti-Feline HRASLS2 monoclonal antibodyFeline
GM-Tg-cang-IP0979-Ab-1/ GM-Tg-cang-IP0979-Ab-2Anti-Canine HRASLS2 monoclonal antibodyCanine
GM-Tg-bovg-IP0979-Ab-1/ GM-Tg-bovg-IP0979-Ab-2Anti-Bovine HRASLS2 monoclonal antibodyBovine
GM-Tg-equg-IP0979-Ab-1/ GM-Tg-equg-IP0979-Ab-2Anti-Equine HRASLS2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0979-Ab-1/ GM-Tg-hg-IP0979-Ab-2; GM-Tg-rg-IP0979-Ab-1/ GM-Tg-rg-IP0979-Ab-2;
GM-Tg-mg-IP0979-Ab-1/ GM-Tg-mg-IP0979-Ab-2; GM-Tg-cynog-IP0979-Ab-1/ GM-Tg-cynog-IP0979-Ab-2;
GM-Tg-felg-IP0979-Ab-1/ GM-Tg-felg-IP0979-Ab-2; GM-Tg-cang-IP0979-Ab-1/ GM-Tg-cang-IP0979-Ab-2;
GM-Tg-bovg-IP0979-Ab-1/ GM-Tg-bovg-IP0979-Ab-2; GM-Tg-equg-IP0979-Ab-1/ GM-Tg-equg-IP0979-Ab-2
Products NameAnti-HRASLS2 monoclonal antibody
Formatmab
Target NameHRASLS2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-HRASLS2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0979-Ag-1Recombinant multi-species PLAT2/ HRASLS2/ PLA1/2-2 protein


    Target information

    Target IDGM-IP0979
    Target NameHRASLS2
    Gene ID54979,722182
    Gene Symbol and SynonymsHRASLS2,PLA1/2-2,PLAAT-2,PLAAT2
    Uniprot AccessionQ9NWW9
    Uniprot Entry NamePLAT2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseBreast Cancer
    Gene EnsemblENSG00000133328
    Target ClassificationN/A

    The target: HRASLS2, gene name: HRASLS2, also named as PLA1/2-2. The protein encoded by this gene has both phospholipase and acyltransferase activities and acts as a tumor suppressor. The encoded protein can hydrolyze dipalmitoylated phosphatidylcholine (PC) to palmitic acid and lyso-PC. In addition, this protein can catalyze the N-acylation of phosphatidylethanolamine and can catalyze the O-acylation of lyso-PC to form PC. [provided by RefSeq, Jul 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.