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Anti-HS3ST3B1 monoclonal antibody
Pre-made anti-HS3ST3B1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HS3ST3B1/HS3ST3B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0983-Ab-1/ GM-Tg-hg-IP0983-Ab-2 | Anti-Human HS3ST3B1 monoclonal antibody | Human |
| GM-Tg-rg-IP0983-Ab-1/ GM-Tg-rg-IP0983-Ab-2 | Anti-Rat HS3ST3B1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0983-Ab-1/ GM-Tg-mg-IP0983-Ab-2 | Anti-Mouse HS3ST3B1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0983-Ab-1/ GM-Tg-cynog-IP0983-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HS3ST3B1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0983-Ab-1/ GM-Tg-felg-IP0983-Ab-2 | Anti-Feline HS3ST3B1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0983-Ab-1/ GM-Tg-cang-IP0983-Ab-2 | Anti-Canine HS3ST3B1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0983-Ab-1/ GM-Tg-bovg-IP0983-Ab-2 | Anti-Bovine HS3ST3B1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0983-Ab-1/ GM-Tg-equg-IP0983-Ab-2 | Anti-Equine HS3ST3B1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0983-Ab-1/ GM-Tg-hg-IP0983-Ab-2; GM-Tg-rg-IP0983-Ab-1/ GM-Tg-rg-IP0983-Ab-2; GM-Tg-mg-IP0983-Ab-1/ GM-Tg-mg-IP0983-Ab-2; GM-Tg-cynog-IP0983-Ab-1/ GM-Tg-cynog-IP0983-Ab-2; GM-Tg-felg-IP0983-Ab-1/ GM-Tg-felg-IP0983-Ab-2; GM-Tg-cang-IP0983-Ab-1/ GM-Tg-cang-IP0983-Ab-2; GM-Tg-bovg-IP0983-Ab-1/ GM-Tg-bovg-IP0983-Ab-2; GM-Tg-equg-IP0983-Ab-1/ GM-Tg-equg-IP0983-Ab-2 |
| Products Name | Anti-HS3ST3B1 monoclonal antibody |
| Format | mab |
| Target Name | HS3ST3B1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HS3ST3B1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0983-Ag-1 | Recombinant multi-species HS3SB/ HS3ST3B1/ 3-OST-3B protein |
Target information
| Target ID | GM-IP0983 |
| Target Name | HS3ST3B1 |
| Gene ID | 9953,303218,100063069 |
| Gene Symbol and Synonyms | 3-OST-3B,3OST3B1,h3-OST-3B,Hs3st3b,HS3ST3B1 |
| Uniprot Accession | Q9Y662 |
| Uniprot Entry Name | HS3SB_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000125430 |
| Target Classification | N/A |
The target: HS3ST3B1, gene name: HS3ST3B1, also named as 3-OST-3B, 3OST3B1, h3-OST-3B. The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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