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Anti-HS3ST4 monoclonal antibody
Pre-made anti-HS3ST4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HS3ST4/HS3ST4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0984-Ab-1/ GM-Tg-hg-IP0984-Ab-2 | Anti-Human HS3ST4 monoclonal antibody | Human |
| GM-Tg-rg-IP0984-Ab-1/ GM-Tg-rg-IP0984-Ab-2 | Anti-Rat HS3ST4 monoclonal antibody | Rat |
| GM-Tg-mg-IP0984-Ab-1/ GM-Tg-mg-IP0984-Ab-2 | Anti-Mouse HS3ST4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0984-Ab-1/ GM-Tg-cynog-IP0984-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HS3ST4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0984-Ab-1/ GM-Tg-felg-IP0984-Ab-2 | Anti-Feline HS3ST4 monoclonal antibody | Feline |
| GM-Tg-cang-IP0984-Ab-1/ GM-Tg-cang-IP0984-Ab-2 | Anti-Canine HS3ST4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0984-Ab-1/ GM-Tg-bovg-IP0984-Ab-2 | Anti-Bovine HS3ST4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0984-Ab-1/ GM-Tg-equg-IP0984-Ab-2 | Anti-Equine HS3ST4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0984-Ab-1/ GM-Tg-hg-IP0984-Ab-2; GM-Tg-rg-IP0984-Ab-1/ GM-Tg-rg-IP0984-Ab-2; GM-Tg-mg-IP0984-Ab-1/ GM-Tg-mg-IP0984-Ab-2; GM-Tg-cynog-IP0984-Ab-1/ GM-Tg-cynog-IP0984-Ab-2; GM-Tg-felg-IP0984-Ab-1/ GM-Tg-felg-IP0984-Ab-2; GM-Tg-cang-IP0984-Ab-1/ GM-Tg-cang-IP0984-Ab-2; GM-Tg-bovg-IP0984-Ab-1/ GM-Tg-bovg-IP0984-Ab-2; GM-Tg-equg-IP0984-Ab-1/ GM-Tg-equg-IP0984-Ab-2 |
| Products Name | Anti-HS3ST4 monoclonal antibody |
| Format | mab |
| Target Name | HS3ST4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HS3ST4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0984-Ag-1 | Recombinant multi-species HS3S4/ HS3ST4/ 3-OST-4 protein |
| ORF Viral Vector | pGMLV000198 | human HS3ST4 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000198 | human HS3ST4 Lentivirus particle |
| ORF Viral Vector | pGMLPm005296 | mouse Hs3st4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005296 | mouse Hs3st4 Lentivirus particle |
Target information
| Target ID | GM-IP0984 |
| Target Name | HS3ST4 |
| Gene ID | 9951,628779,108349781,703383,489960,101087442,104968447 |
| Gene Symbol and Synonyms | 3-OST-4,30ST4,3OST4,Gm6915,h3-OST-4,HS3ST4 |
| Uniprot Accession | Q9Y661 |
| Uniprot Entry Name | HS3S4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000182601 |
| Target Classification | N/A |
The target: HS3ST4, gene name: HS3ST4, also named as 3-OST-4, 30ST4, 3OST4, h3-OST-4. This gene encodes the enzyme heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4. This enzyme generates 3-O-sulfated glucosaminyl residues in heparan sulfate. Cell surface heparan sulfate is used as a receptor by herpes simplex virus type 1 (HSV-1), and expression of this gene is thought to play a role in HSV-1 pathogenesis. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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