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Anti-HYAL4 monoclonal antibody
Pre-made anti-HYAL4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HYAL4/HYAL4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0993-Ab-1/ GM-Tg-hg-IP0993-Ab-2 | Anti-Human HYAL4 monoclonal antibody | Human |
| GM-Tg-rg-IP0993-Ab-1/ GM-Tg-rg-IP0993-Ab-2 | Anti-Rat HYAL4 monoclonal antibody | Rat |
| GM-Tg-mg-IP0993-Ab-1/ GM-Tg-mg-IP0993-Ab-2 | Anti-Mouse HYAL4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0993-Ab-1/ GM-Tg-cynog-IP0993-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HYAL4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0993-Ab-1/ GM-Tg-felg-IP0993-Ab-2 | Anti-Feline HYAL4 monoclonal antibody | Feline |
| GM-Tg-cang-IP0993-Ab-1/ GM-Tg-cang-IP0993-Ab-2 | Anti-Canine HYAL4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0993-Ab-1/ GM-Tg-bovg-IP0993-Ab-2 | Anti-Bovine HYAL4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0993-Ab-1/ GM-Tg-equg-IP0993-Ab-2 | Anti-Equine HYAL4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0993-Ab-1/ GM-Tg-hg-IP0993-Ab-2; GM-Tg-rg-IP0993-Ab-1/ GM-Tg-rg-IP0993-Ab-2; GM-Tg-mg-IP0993-Ab-1/ GM-Tg-mg-IP0993-Ab-2; GM-Tg-cynog-IP0993-Ab-1/ GM-Tg-cynog-IP0993-Ab-2; GM-Tg-felg-IP0993-Ab-1/ GM-Tg-felg-IP0993-Ab-2; GM-Tg-cang-IP0993-Ab-1/ GM-Tg-cang-IP0993-Ab-2; GM-Tg-bovg-IP0993-Ab-1/ GM-Tg-bovg-IP0993-Ab-2; GM-Tg-equg-IP0993-Ab-1/ GM-Tg-equg-IP0993-Ab-2 |
| Products Name | Anti-HYAL4 monoclonal antibody |
| Format | mab |
| Target Name | HYAL4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HYAL4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0993-Ag-1 | Recombinant multi-species HYAL4/ CSHY protein |
Target information
| Target ID | GM-IP0993 |
| Target Name | HYAL4 |
| Gene ID | 23553,77042,404783,696805,518161,100056514 |
| Gene Symbol and Synonyms | 4632428M18Rik,CSHY,HYAL-4,HYAL4 |
| Uniprot Accession | Q2M3T9 |
| Uniprot Entry Name | HYAL4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000106302 |
| Target Classification | N/A |
The target: HYAL4, gene name: HYAL4, also named as CSHY. This gene encodes a protein which is similar in structure to hyaluronidases but lacks hyaluronidase activity. The encoded protein acts as a chondroitin-sulfate-specific endo-beta-N-acetylgalactosaminidase; that is, it exhibits hydrolytic activity toward chondroitin sulfate chains and degrades them into oligosaccharides. Proteoglycans are formed by the covalent linkage of chondroitin sulfate chains to protein. Proteoglycans are ubiquitous components of the extracellular matrix of connective tissues and are also found at the surface of many cell types where they participate in a variety of cellular processes such as cell proliferation, differentiation, migration, cell-cell recognition, extracellular matrix deposition, and tissue morphogenesis. The expression of this gene is highest in testes and placenta. [provided by RefSeq, Apr 2019].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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