Anti-JAGN1 monoclonal antibody

Pre-made anti-JAGN1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to JAGN1/JAGN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1028-Ab-1/ GM-Tg-hg-IP1028-Ab-2Anti-Human JAGN1 monoclonal antibodyHuman
GM-Tg-rg-IP1028-Ab-1/ GM-Tg-rg-IP1028-Ab-2Anti-Rat JAGN1 monoclonal antibodyRat
GM-Tg-mg-IP1028-Ab-1/ GM-Tg-mg-IP1028-Ab-2Anti-Mouse JAGN1 monoclonal antibodyMouse
GM-Tg-cynog-IP1028-Ab-1/ GM-Tg-cynog-IP1028-Ab-2Anti-Cynomolgus/ Rhesus macaque JAGN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1028-Ab-1/ GM-Tg-felg-IP1028-Ab-2Anti-Feline JAGN1 monoclonal antibodyFeline
GM-Tg-cang-IP1028-Ab-1/ GM-Tg-cang-IP1028-Ab-2Anti-Canine JAGN1 monoclonal antibodyCanine
GM-Tg-bovg-IP1028-Ab-1/ GM-Tg-bovg-IP1028-Ab-2Anti-Bovine JAGN1 monoclonal antibodyBovine
GM-Tg-equg-IP1028-Ab-1/ GM-Tg-equg-IP1028-Ab-2Anti-Equine JAGN1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1028-Ab-1/ GM-Tg-hg-IP1028-Ab-2; GM-Tg-rg-IP1028-Ab-1/ GM-Tg-rg-IP1028-Ab-2;
GM-Tg-mg-IP1028-Ab-1/ GM-Tg-mg-IP1028-Ab-2; GM-Tg-cynog-IP1028-Ab-1/ GM-Tg-cynog-IP1028-Ab-2;
GM-Tg-felg-IP1028-Ab-1/ GM-Tg-felg-IP1028-Ab-2; GM-Tg-cang-IP1028-Ab-1/ GM-Tg-cang-IP1028-Ab-2;
GM-Tg-bovg-IP1028-Ab-1/ GM-Tg-bovg-IP1028-Ab-2; GM-Tg-equg-IP1028-Ab-1/ GM-Tg-equg-IP1028-Ab-2
Products NameAnti-JAGN1 monoclonal antibody
Formatmab
Target NameJAGN1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-JAGN1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1028-Ag-1Recombinant multi-species JAGN1/ GL009/ SCN6 protein


    Target information

    Target IDGM-IP1028
    Target NameJAGN1
    Gene ID84522,67767,502872,699718,106557473,101085870,539101,100052115
    Gene Symbol and Synonyms5830427H10Rik,GL009,JAGN1,SCN6
    Uniprot AccessionQ8N5M9,Q4KM64,Q2NKY9
    Uniprot Entry NameJAGN1_HUMAN,JAGN1_RAT,JAGN1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000171135
    Target ClassificationN/A

    The target: JAGN1, gene name: JAGN1, also named as GL009, SCN6. The protein encoded by this gene is a transmembrane protein. It functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Mutations in this gene result in severe congenital neutropenia. [provided by RefSeq, Oct 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.