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Anti-KCNK5 monoclonal antibody
Pre-made anti-KCNK5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to KCNK5/KCNK5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1038-Ab-1/ GM-Tg-hg-IP1038-Ab-2 | Anti-Human KCNK5 monoclonal antibody | Human |
| GM-Tg-rg-IP1038-Ab-1/ GM-Tg-rg-IP1038-Ab-2 | Anti-Rat KCNK5 monoclonal antibody | Rat |
| GM-Tg-mg-IP1038-Ab-1/ GM-Tg-mg-IP1038-Ab-2 | Anti-Mouse KCNK5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1038-Ab-1/ GM-Tg-cynog-IP1038-Ab-2 | Anti-Cynomolgus/ Rhesus macaque KCNK5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1038-Ab-1/ GM-Tg-felg-IP1038-Ab-2 | Anti-Feline KCNK5 monoclonal antibody | Feline |
| GM-Tg-cang-IP1038-Ab-1/ GM-Tg-cang-IP1038-Ab-2 | Anti-Canine KCNK5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1038-Ab-1/ GM-Tg-bovg-IP1038-Ab-2 | Anti-Bovine KCNK5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1038-Ab-1/ GM-Tg-equg-IP1038-Ab-2 | Anti-Equine KCNK5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1038-Ab-1/ GM-Tg-hg-IP1038-Ab-2; GM-Tg-rg-IP1038-Ab-1/ GM-Tg-rg-IP1038-Ab-2; GM-Tg-mg-IP1038-Ab-1/ GM-Tg-mg-IP1038-Ab-2; GM-Tg-cynog-IP1038-Ab-1/ GM-Tg-cynog-IP1038-Ab-2; GM-Tg-felg-IP1038-Ab-1/ GM-Tg-felg-IP1038-Ab-2; GM-Tg-cang-IP1038-Ab-1/ GM-Tg-cang-IP1038-Ab-2; GM-Tg-bovg-IP1038-Ab-1/ GM-Tg-bovg-IP1038-Ab-2; GM-Tg-equg-IP1038-Ab-1/ GM-Tg-equg-IP1038-Ab-2 |
| Products Name | Anti-KCNK5 monoclonal antibody |
| Format | mab |
| Target Name | KCNK5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-KCNK5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1038-Ag-1 | Recombinant multi-species KCNK5/ K2p5.1b/ TASK-2 protein |
| ORF Viral Vector | vGMLP002854 | human KCNK5 Lentivirus particle |
| ORF Viral Vector | pGMLP002854 | human KCNK5 Lentivirus plasmid |
Target information
| Target ID | GM-IP1038 |
| Target Name | KCNK5 |
| Gene ID | 8645,16529,364241,719563,481780,101085375,782166,100065337 |
| Gene Symbol and Synonyms | K2p5.1,KCNK5,KCNK5b,TASK-2,TASK2 |
| Uniprot Accession | O95279 |
| Uniprot Entry Name | KCNK5_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000164626 |
| Target Classification | N/A |
The target: KCNK5, gene name: KCNK5, also named as K2p5.1b, TASK-2, TASK2, KCNK5. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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