Anti-RIC1 monoclonal antibody

Pre-made anti-RIC1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to RIC1/RIC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1048-Ab-1/ GM-Tg-hg-IP1048-Ab-2Anti-Human RIC1 monoclonal antibodyHuman
GM-Tg-rg-IP1048-Ab-1/ GM-Tg-rg-IP1048-Ab-2Anti-Rat RIC1 monoclonal antibodyRat
GM-Tg-mg-IP1048-Ab-1/ GM-Tg-mg-IP1048-Ab-2Anti-Mouse RIC1 monoclonal antibodyMouse
GM-Tg-cynog-IP1048-Ab-1/ GM-Tg-cynog-IP1048-Ab-2Anti-Cynomolgus/ Rhesus macaque RIC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1048-Ab-1/ GM-Tg-felg-IP1048-Ab-2Anti-Feline RIC1 monoclonal antibodyFeline
GM-Tg-cang-IP1048-Ab-1/ GM-Tg-cang-IP1048-Ab-2Anti-Canine RIC1 monoclonal antibodyCanine
GM-Tg-bovg-IP1048-Ab-1/ GM-Tg-bovg-IP1048-Ab-2Anti-Bovine RIC1 monoclonal antibodyBovine
GM-Tg-equg-IP1048-Ab-1/ GM-Tg-equg-IP1048-Ab-2Anti-Equine RIC1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1048-Ab-1/ GM-Tg-hg-IP1048-Ab-2; GM-Tg-rg-IP1048-Ab-1/ GM-Tg-rg-IP1048-Ab-2;
GM-Tg-mg-IP1048-Ab-1/ GM-Tg-mg-IP1048-Ab-2; GM-Tg-cynog-IP1048-Ab-1/ GM-Tg-cynog-IP1048-Ab-2;
GM-Tg-felg-IP1048-Ab-1/ GM-Tg-felg-IP1048-Ab-2; GM-Tg-cang-IP1048-Ab-1/ GM-Tg-cang-IP1048-Ab-2;
GM-Tg-bovg-IP1048-Ab-1/ GM-Tg-bovg-IP1048-Ab-2; GM-Tg-equg-IP1048-Ab-1/ GM-Tg-equg-IP1048-Ab-2
Products NameAnti-RIC1 monoclonal antibody
Formatmab
Target NameRIC1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-RIC1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1048-Ag-1Recombinant multi-species RIC1/ CIP150/ KIAA1432 protein


    Target information

    Target IDGM-IP1048
    Target NameRIC1
    Gene ID57589,226089,309306,717435,484187,101088439,506005,100059612
    Gene Symbol and SynonymsbA207C16.1,C030046E11Rik,C130057E09Rik,CATIFA,CIP150,KIAA1432,RGD1310016,RIC1
    Uniprot AccessionQ4ADV7
    Uniprot Entry NameRIC1_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000107036
    Target ClassificationN/A

    The target: RIC1, gene name: RIC1, also named as CIP150, KIAA1432, bA207C16.1. Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including positive regulation of GTPase activity; regulation of extracellular matrix constituent secretion; and retrograde transport, endosome to Golgi. Located in cytosol and membrane. Part of Ric1-Rgp1 guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.