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Anti-LARP4B monoclonal antibody
Pre-made anti-LARP4B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LARP4B/LARP4B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1069-Ab-1/ GM-Tg-hg-IP1069-Ab-2 | Anti-Human LARP4B monoclonal antibody | Human |
| GM-Tg-rg-IP1069-Ab-1/ GM-Tg-rg-IP1069-Ab-2 | Anti-Rat LARP4B monoclonal antibody | Rat |
| GM-Tg-mg-IP1069-Ab-1/ GM-Tg-mg-IP1069-Ab-2 | Anti-Mouse LARP4B monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1069-Ab-1/ GM-Tg-cynog-IP1069-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LARP4B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1069-Ab-1/ GM-Tg-felg-IP1069-Ab-2 | Anti-Feline LARP4B monoclonal antibody | Feline |
| GM-Tg-cang-IP1069-Ab-1/ GM-Tg-cang-IP1069-Ab-2 | Anti-Canine LARP4B monoclonal antibody | Canine |
| GM-Tg-bovg-IP1069-Ab-1/ GM-Tg-bovg-IP1069-Ab-2 | Anti-Bovine LARP4B monoclonal antibody | Bovine |
| GM-Tg-equg-IP1069-Ab-1/ GM-Tg-equg-IP1069-Ab-2 | Anti-Equine LARP4B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1069-Ab-1/ GM-Tg-hg-IP1069-Ab-2; GM-Tg-rg-IP1069-Ab-1/ GM-Tg-rg-IP1069-Ab-2; GM-Tg-mg-IP1069-Ab-1/ GM-Tg-mg-IP1069-Ab-2; GM-Tg-cynog-IP1069-Ab-1/ GM-Tg-cynog-IP1069-Ab-2; GM-Tg-felg-IP1069-Ab-1/ GM-Tg-felg-IP1069-Ab-2; GM-Tg-cang-IP1069-Ab-1/ GM-Tg-cang-IP1069-Ab-2; GM-Tg-bovg-IP1069-Ab-1/ GM-Tg-bovg-IP1069-Ab-2; GM-Tg-equg-IP1069-Ab-1/ GM-Tg-equg-IP1069-Ab-2 |
| Products Name | Anti-LARP4B monoclonal antibody |
| Format | mab |
| Target Name | LARP4B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LARP4B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1069-Ag-1 | Recombinant multi-species LAR4B/ LARP4B/ KIAA0217 protein |
| ORF Viral Vector | vGMLP003259 | human LARP4B Lentivirus particle |
| ORF Viral Vector | pGMLP003259 | human LARP4B Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003669 | mouse Larp4b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003669 | mouse Larp4b Lentivirus particle |
Target information
| Target ID | GM-IP1069 |
| Target Name | LARP4B |
| Gene ID | 23185,217980,307070,721993,478022,101095267,505723,100057616 |
| Gene Symbol and Synonyms | A630096F19,D13Wsu64e,KIAA0217,LARP4B,LARP5,RGD1310713 |
| Uniprot Accession | Q92615 |
| Uniprot Entry Name | LAR4B_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000107929 |
| Target Classification | N/A |
The target: LARP4B, gene name: LARP4B, also named as KIAA0217, LARP5. This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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