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Anti-LEPROTL1 monoclonal antibody
Pre-made anti-LEPROTL1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LEPROTL1/LEPROTL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1081-Ab-1/ GM-Tg-hg-IP1081-Ab-2 | Anti-Human LEPROTL1 monoclonal antibody | Human |
| GM-Tg-rg-IP1081-Ab-1/ GM-Tg-rg-IP1081-Ab-2 | Anti-Rat LEPROTL1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1081-Ab-1/ GM-Tg-mg-IP1081-Ab-2 | Anti-Mouse LEPROTL1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1081-Ab-1/ GM-Tg-cynog-IP1081-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LEPROTL1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1081-Ab-1/ GM-Tg-felg-IP1081-Ab-2 | Anti-Feline LEPROTL1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1081-Ab-1/ GM-Tg-cang-IP1081-Ab-2 | Anti-Canine LEPROTL1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1081-Ab-1/ GM-Tg-bovg-IP1081-Ab-2 | Anti-Bovine LEPROTL1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1081-Ab-1/ GM-Tg-equg-IP1081-Ab-2 | Anti-Equine LEPROTL1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1081-Ab-1/ GM-Tg-hg-IP1081-Ab-2; GM-Tg-rg-IP1081-Ab-1/ GM-Tg-rg-IP1081-Ab-2; GM-Tg-mg-IP1081-Ab-1/ GM-Tg-mg-IP1081-Ab-2; GM-Tg-cynog-IP1081-Ab-1/ GM-Tg-cynog-IP1081-Ab-2; GM-Tg-felg-IP1081-Ab-1/ GM-Tg-felg-IP1081-Ab-2; GM-Tg-cang-IP1081-Ab-1/ GM-Tg-cang-IP1081-Ab-2; GM-Tg-bovg-IP1081-Ab-1/ GM-Tg-bovg-IP1081-Ab-2; GM-Tg-equg-IP1081-Ab-1/ GM-Tg-equg-IP1081-Ab-2 |
| Products Name | Anti-LEPROTL1 monoclonal antibody |
| Format | mab |
| Target Name | LEPROTL1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LEPROTL1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1081-Ag-1 | Recombinant multi-species LERL1/ LEPROTL1/ HSPC112 protein |
| ORF Viral Vector | pGMLP003268 | human LEPROTL1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003268 | human LEPROTL1 Lentivirus particle |
| ORF Viral Vector | pGMLPm002368 | mouse Leprotl1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002368 | mouse Leprotl1 Lentivirus particle |
Target information
| Target ID | GM-IP1081 |
| Target Name | LEPROTL1 |
| Gene ID | 23484,68192,361160,694012,475601,101093431,513036,100062721 |
| Gene Symbol and Synonyms | 1110067H13Rik,1520402O14Rik,HSPC112,LEPROTL1,my047,Vps55 |
| Uniprot Accession | O95214,Q6PDU4,Q32PD8 |
| Uniprot Entry Name | LERL1_HUMAN,LERL1_RAT,LERL1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000104660 |
| Target Classification | N/A |
The target: LEPROTL1, gene name: LEPROTL1, also named as HSPC112, Vps55, my047. Enables identical protein binding activity. Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and negative regulation of growth hormone receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be active in endosome. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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