Anti-LMAN1L monoclonal antibody

Pre-made anti-LMAN1L monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to LMAN1L/LMAN1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1090-Ab-1/ GM-Tg-hg-IP1090-Ab-2Anti-Human LMAN1L monoclonal antibodyHuman
GM-Tg-rg-IP1090-Ab-1/ GM-Tg-rg-IP1090-Ab-2Anti-Rat LMAN1L monoclonal antibodyRat
GM-Tg-mg-IP1090-Ab-1/ GM-Tg-mg-IP1090-Ab-2Anti-Mouse LMAN1L monoclonal antibodyMouse
GM-Tg-cynog-IP1090-Ab-1/ GM-Tg-cynog-IP1090-Ab-2Anti-Cynomolgus/ Rhesus macaque LMAN1L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1090-Ab-1/ GM-Tg-felg-IP1090-Ab-2Anti-Feline LMAN1L monoclonal antibodyFeline
GM-Tg-cang-IP1090-Ab-1/ GM-Tg-cang-IP1090-Ab-2Anti-Canine LMAN1L monoclonal antibodyCanine
GM-Tg-bovg-IP1090-Ab-1/ GM-Tg-bovg-IP1090-Ab-2Anti-Bovine LMAN1L monoclonal antibodyBovine
GM-Tg-equg-IP1090-Ab-1/ GM-Tg-equg-IP1090-Ab-2Anti-Equine LMAN1L monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1090-Ab-1/ GM-Tg-hg-IP1090-Ab-2; GM-Tg-rg-IP1090-Ab-1/ GM-Tg-rg-IP1090-Ab-2;
GM-Tg-mg-IP1090-Ab-1/ GM-Tg-mg-IP1090-Ab-2; GM-Tg-cynog-IP1090-Ab-1/ GM-Tg-cynog-IP1090-Ab-2;
GM-Tg-felg-IP1090-Ab-1/ GM-Tg-felg-IP1090-Ab-2; GM-Tg-cang-IP1090-Ab-1/ GM-Tg-cang-IP1090-Ab-2;
GM-Tg-bovg-IP1090-Ab-1/ GM-Tg-bovg-IP1090-Ab-2; GM-Tg-equg-IP1090-Ab-1/ GM-Tg-equg-IP1090-Ab-2
Products NameAnti-LMAN1L monoclonal antibody
Formatmab
Target NameLMAN1L
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-LMAN1L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1090-Ag-1Recombinant multi-species LMA1L/ LMAN1L/ ERGIC-53L protein


    Target information

    Target IDGM-IP1090
    Target NameLMAN1L
    Gene ID79748,235416,300743,709457,487650,101085128,617152,100062212
    Gene Symbol and SynonymsERGIC-53L,ERGL,LMAN1L,slamp
    Uniprot AccessionQ9HAT1,Q5FB95
    Uniprot Entry NameLMA1L_HUMAN,LMA1L_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000140506
    Target ClassificationN/A

    The target: LMAN1L, gene name: LMAN1L, also named as ERGIC-53L, ERGL. This gene encodes a mannose-binding type 1 transmembrane protein that contains an N-terminal lectin-like carbohydrate recognition domain. The encoded protein is similar in structure to lectins found in leguminous plants. This lectin is thought to transport newly synthesized glycoproteins from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment. [provided by RefSeq, Jan 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.