Anti-LMAN2 monoclonal antibody

Pre-made anti-LMAN2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to LMAN2/LMAN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1091-Ab-1/ GM-Tg-hg-IP1091-Ab-2Anti-Human LMAN2 monoclonal antibodyHuman
GM-Tg-rg-IP1091-Ab-1/ GM-Tg-rg-IP1091-Ab-2Anti-Rat LMAN2 monoclonal antibodyRat
GM-Tg-mg-IP1091-Ab-1/ GM-Tg-mg-IP1091-Ab-2Anti-Mouse LMAN2 monoclonal antibodyMouse
GM-Tg-cynog-IP1091-Ab-1/ GM-Tg-cynog-IP1091-Ab-2Anti-Cynomolgus/ Rhesus macaque LMAN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1091-Ab-1/ GM-Tg-felg-IP1091-Ab-2Anti-Feline LMAN2 monoclonal antibodyFeline
GM-Tg-cang-IP1091-Ab-1/ GM-Tg-cang-IP1091-Ab-2Anti-Canine LMAN2 monoclonal antibodyCanine
GM-Tg-bovg-IP1091-Ab-1/ GM-Tg-bovg-IP1091-Ab-2Anti-Bovine LMAN2 monoclonal antibodyBovine
GM-Tg-equg-IP1091-Ab-1/ GM-Tg-equg-IP1091-Ab-2Anti-Equine LMAN2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1091-Ab-1/ GM-Tg-hg-IP1091-Ab-2; GM-Tg-rg-IP1091-Ab-1/ GM-Tg-rg-IP1091-Ab-2;
GM-Tg-mg-IP1091-Ab-1/ GM-Tg-mg-IP1091-Ab-2; GM-Tg-cynog-IP1091-Ab-1/ GM-Tg-cynog-IP1091-Ab-2;
GM-Tg-felg-IP1091-Ab-1/ GM-Tg-felg-IP1091-Ab-2; GM-Tg-cang-IP1091-Ab-1/ GM-Tg-cang-IP1091-Ab-2;
GM-Tg-bovg-IP1091-Ab-1/ GM-Tg-bovg-IP1091-Ab-2; GM-Tg-equg-IP1091-Ab-1/ GM-Tg-equg-IP1091-Ab-2
Products NameAnti-LMAN2 monoclonal antibody
Formatmab
Target NameLMAN2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-LMAN2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1091-Ag-1Recombinant multi-species LMAN2/ C5orf8/ GP36B protein


    Target information

    Target IDGM-IP1091
    Target NameLMAN2
    Gene ID10960,66890,290994,723005,403938,101099687,790870,100058443
    Gene Symbol and Synonyms1110003H06Rik,1300009F09Rik,C5orf8,GP36B,LMAN2,VIP36
    Uniprot AccessionQ12907,P49256
    Uniprot Entry NameLMAN2_HUMAN,LMAN2_CANLF
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169223
    Target ClassificationN/A

    The target: LMAN2, gene name: LMAN2, also named as C5orf8, GP36B, VIP36. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq, Oct 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.