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Anti-LMAN2L monoclonal antibody
Pre-made anti-LMAN2L monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LMAN2L/LMAN2L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1092-Ab-1/ GM-Tg-hg-IP1092-Ab-2 | Anti-Human LMAN2L monoclonal antibody | Human |
| GM-Tg-rg-IP1092-Ab-1/ GM-Tg-rg-IP1092-Ab-2 | Anti-Rat LMAN2L monoclonal antibody | Rat |
| GM-Tg-mg-IP1092-Ab-1/ GM-Tg-mg-IP1092-Ab-2 | Anti-Mouse LMAN2L monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1092-Ab-1/ GM-Tg-cynog-IP1092-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LMAN2L monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1092-Ab-1/ GM-Tg-felg-IP1092-Ab-2 | Anti-Feline LMAN2L monoclonal antibody | Feline |
| GM-Tg-cang-IP1092-Ab-1/ GM-Tg-cang-IP1092-Ab-2 | Anti-Canine LMAN2L monoclonal antibody | Canine |
| GM-Tg-bovg-IP1092-Ab-1/ GM-Tg-bovg-IP1092-Ab-2 | Anti-Bovine LMAN2L monoclonal antibody | Bovine |
| GM-Tg-equg-IP1092-Ab-1/ GM-Tg-equg-IP1092-Ab-2 | Anti-Equine LMAN2L monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1092-Ab-1/ GM-Tg-hg-IP1092-Ab-2; GM-Tg-rg-IP1092-Ab-1/ GM-Tg-rg-IP1092-Ab-2; GM-Tg-mg-IP1092-Ab-1/ GM-Tg-mg-IP1092-Ab-2; GM-Tg-cynog-IP1092-Ab-1/ GM-Tg-cynog-IP1092-Ab-2; GM-Tg-felg-IP1092-Ab-1/ GM-Tg-felg-IP1092-Ab-2; GM-Tg-cang-IP1092-Ab-1/ GM-Tg-cang-IP1092-Ab-2; GM-Tg-bovg-IP1092-Ab-1/ GM-Tg-bovg-IP1092-Ab-2; GM-Tg-equg-IP1092-Ab-1/ GM-Tg-equg-IP1092-Ab-2 |
| Products Name | Anti-LMAN2L monoclonal antibody |
| Format | mab |
| Target Name | LMAN2L |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LMAN2L monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1092-Ag-1 | Recombinant multi-species LMA2L/ LMAN2L/ MRT52 protein |
Target information
| Target ID | GM-IP1092 |
| Target Name | LMAN2L |
| Gene ID | 81562,214895,301343,706379,474569,101091780,539289,100051330 |
| Gene Symbol and Synonyms | A630028F14Rik,LMAN2L,MRD69,MRT52,VIP36-like,VIPL |
| Uniprot Accession | Q9H0V9,Q2HJD1 |
| Uniprot Entry Name | LMA2L_HUMAN,LMA2L_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000114988 |
| Target Classification | N/A |
The target: LMAN2L, gene name: LMAN2L, also named as MRT52, VIPL. This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway. [provided by RefSeq, Apr 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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