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Anti-LMBR1 monoclonal antibody
Pre-made anti-LMBR1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LMBR1/LMBR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1093-Ab-1/ GM-Tg-hg-IP1093-Ab-2 | Anti-Human LMBR1 monoclonal antibody | Human |
| GM-Tg-rg-IP1093-Ab-1/ GM-Tg-rg-IP1093-Ab-2 | Anti-Rat LMBR1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1093-Ab-1/ GM-Tg-mg-IP1093-Ab-2 | Anti-Mouse LMBR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1093-Ab-1/ GM-Tg-cynog-IP1093-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LMBR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1093-Ab-1/ GM-Tg-felg-IP1093-Ab-2 | Anti-Feline LMBR1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1093-Ab-1/ GM-Tg-cang-IP1093-Ab-2 | Anti-Canine LMBR1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1093-Ab-1/ GM-Tg-bovg-IP1093-Ab-2 | Anti-Bovine LMBR1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1093-Ab-1/ GM-Tg-equg-IP1093-Ab-2 | Anti-Equine LMBR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1093-Ab-1/ GM-Tg-hg-IP1093-Ab-2; GM-Tg-rg-IP1093-Ab-1/ GM-Tg-rg-IP1093-Ab-2; GM-Tg-mg-IP1093-Ab-1/ GM-Tg-mg-IP1093-Ab-2; GM-Tg-cynog-IP1093-Ab-1/ GM-Tg-cynog-IP1093-Ab-2; GM-Tg-felg-IP1093-Ab-1/ GM-Tg-felg-IP1093-Ab-2; GM-Tg-cang-IP1093-Ab-1/ GM-Tg-cang-IP1093-Ab-2; GM-Tg-bovg-IP1093-Ab-1/ GM-Tg-bovg-IP1093-Ab-2; GM-Tg-equg-IP1093-Ab-1/ GM-Tg-equg-IP1093-Ab-2 |
| Products Name | Anti-LMBR1 monoclonal antibody |
| Format | mab |
| Target Name | LMBR1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LMBR1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1093-Ag-1 | Recombinant multi-species LMBR1/ ACHP/ C7orf2 protein |
Target information
| Target ID | GM-IP1093 |
| Target Name | LMBR1 |
| Gene ID | 64327,56873,362295,719766,482819,101088917,519337,100066736 |
| Gene Symbol and Synonyms | 1110048D14Rik,ACHP,C7orf2,DIF14,LMBR1,LSS,PPD2,RGD1563910,THYP,TPT,TPTPS,ZRS |
| Uniprot Accession | Q8WVP7 |
| Uniprot Entry Name | LMBR1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000105983 |
| Target Classification | N/A |
The target: LMBR1, gene name: LMBR1, also named as ACHP, C7orf2, DIF14, LSS, PPD2, THYP, TPT, ZRS. This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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