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Anti-LMTK2 monoclonal antibody
Pre-made anti-LMTK2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LMTK2/LMTK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1099-Ab-1/ GM-Tg-hg-IP1099-Ab-2 | Anti-Human LMTK2 monoclonal antibody | Human |
| GM-Tg-rg-IP1099-Ab-1/ GM-Tg-rg-IP1099-Ab-2 | Anti-Rat LMTK2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1099-Ab-1/ GM-Tg-mg-IP1099-Ab-2 | Anti-Mouse LMTK2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1099-Ab-1/ GM-Tg-cynog-IP1099-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LMTK2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1099-Ab-1/ GM-Tg-felg-IP1099-Ab-2 | Anti-Feline LMTK2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1099-Ab-1/ GM-Tg-cang-IP1099-Ab-2 | Anti-Canine LMTK2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1099-Ab-1/ GM-Tg-bovg-IP1099-Ab-2 | Anti-Bovine LMTK2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1099-Ab-1/ GM-Tg-equg-IP1099-Ab-2 | Anti-Equine LMTK2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1099-Ab-1/ GM-Tg-hg-IP1099-Ab-2; GM-Tg-rg-IP1099-Ab-1/ GM-Tg-rg-IP1099-Ab-2; GM-Tg-mg-IP1099-Ab-1/ GM-Tg-mg-IP1099-Ab-2; GM-Tg-cynog-IP1099-Ab-1/ GM-Tg-cynog-IP1099-Ab-2; GM-Tg-felg-IP1099-Ab-1/ GM-Tg-felg-IP1099-Ab-2; GM-Tg-cang-IP1099-Ab-1/ GM-Tg-cang-IP1099-Ab-2; GM-Tg-bovg-IP1099-Ab-1/ GM-Tg-bovg-IP1099-Ab-2; GM-Tg-equg-IP1099-Ab-1/ GM-Tg-equg-IP1099-Ab-2 |
| Products Name | Anti-LMTK2 monoclonal antibody |
| Format | mab |
| Target Name | LMTK2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LMTK2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1099-Ag-1 | Recombinant multi-species LMTK2/ AATYK2/ BREK protein |
Target information
| Target ID | GM-IP1099 |
| Target Name | LMTK2 |
| Gene ID | 22853,231876,304286,718147,608946,101097774,512290,100629931 |
| Gene Symbol and Synonyms | 2900041G10Rik,A330101P12Rik,AATYK2,BREK,cprk,hBREK,KPI-2,KPI2,LMR2,LMTK2,PPP1R100 |
| Uniprot Accession | Q8IWU2 |
| Uniprot Entry Name | LMTK2_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000164715 |
| Target Classification | Kinase |
The target: LMTK2, gene name: LMTK2, also named as AATYK2, BREK, KPI-2, KPI2, LMR2, PPP1R100, cprk, hBREK. The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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