Anti-LRRC38 monoclonal antibody

Pre-made anti-LRRC38 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to LRRC38/LRRC38 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1118-Ab-1/ GM-Tg-hg-IP1118-Ab-2Anti-Human LRRC38 monoclonal antibodyHuman
GM-Tg-rg-IP1118-Ab-1/ GM-Tg-rg-IP1118-Ab-2Anti-Rat LRRC38 monoclonal antibodyRat
GM-Tg-mg-IP1118-Ab-1/ GM-Tg-mg-IP1118-Ab-2Anti-Mouse LRRC38 monoclonal antibodyMouse
GM-Tg-cynog-IP1118-Ab-1/ GM-Tg-cynog-IP1118-Ab-2Anti-Cynomolgus/ Rhesus macaque LRRC38 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1118-Ab-1/ GM-Tg-felg-IP1118-Ab-2Anti-Feline LRRC38 monoclonal antibodyFeline
GM-Tg-cang-IP1118-Ab-1/ GM-Tg-cang-IP1118-Ab-2Anti-Canine LRRC38 monoclonal antibodyCanine
GM-Tg-bovg-IP1118-Ab-1/ GM-Tg-bovg-IP1118-Ab-2Anti-Bovine LRRC38 monoclonal antibodyBovine
GM-Tg-equg-IP1118-Ab-1/ GM-Tg-equg-IP1118-Ab-2Anti-Equine LRRC38 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1118-Ab-1/ GM-Tg-hg-IP1118-Ab-2; GM-Tg-rg-IP1118-Ab-1/ GM-Tg-rg-IP1118-Ab-2;
GM-Tg-mg-IP1118-Ab-1/ GM-Tg-mg-IP1118-Ab-2; GM-Tg-cynog-IP1118-Ab-1/ GM-Tg-cynog-IP1118-Ab-2;
GM-Tg-felg-IP1118-Ab-1/ GM-Tg-felg-IP1118-Ab-2; GM-Tg-cang-IP1118-Ab-1/ GM-Tg-cang-IP1118-Ab-2;
GM-Tg-bovg-IP1118-Ab-1/ GM-Tg-bovg-IP1118-Ab-2; GM-Tg-equg-IP1118-Ab-1/ GM-Tg-equg-IP1118-Ab-2
Products NameAnti-LRRC38 monoclonal antibody
Formatmab
Target NameLRRC38
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-LRRC38 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1118-Ag-1Recombinant multi-species LRC38/ LRRC38 protein


    Target information

    Target IDGM-IP1118
    Target NameLRRC38
    Gene ID126755,242735,313681,722785,487434,101081649,789209,102148312
    Gene Symbol and SynonymsA230053A07Rik,LRRC38,RGD1311416
    Uniprot AccessionQ5VT99
    Uniprot Entry NameLRC38_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162494
    Target ClassificationIon Channel

    The target: LRRC38, gene name: LRRC38, also named as . Enables potassium channel activator activity and transmembrane transporter binding activity. Involved in positive regulation of voltage-gated potassium channel activity and potassium ion transmembrane transport. Part of voltage-gated potassium channel complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.