Anti-LRRC52 monoclonal antibody

Pre-made anti-LRRC52 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to LRRC52/LRRC52 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1119-Ab-1/ GM-Tg-hg-IP1119-Ab-2Anti-Human LRRC52 monoclonal antibodyHuman
GM-Tg-rg-IP1119-Ab-1/ GM-Tg-rg-IP1119-Ab-2Anti-Rat LRRC52 monoclonal antibodyRat
GM-Tg-mg-IP1119-Ab-1/ GM-Tg-mg-IP1119-Ab-2Anti-Mouse LRRC52 monoclonal antibodyMouse
GM-Tg-cynog-IP1119-Ab-1/ GM-Tg-cynog-IP1119-Ab-2Anti-Cynomolgus/ Rhesus macaque LRRC52 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1119-Ab-1/ GM-Tg-felg-IP1119-Ab-2Anti-Feline LRRC52 monoclonal antibodyFeline
GM-Tg-cang-IP1119-Ab-1/ GM-Tg-cang-IP1119-Ab-2Anti-Canine LRRC52 monoclonal antibodyCanine
GM-Tg-bovg-IP1119-Ab-1/ GM-Tg-bovg-IP1119-Ab-2Anti-Bovine LRRC52 monoclonal antibodyBovine
GM-Tg-equg-IP1119-Ab-1/ GM-Tg-equg-IP1119-Ab-2Anti-Equine LRRC52 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1119-Ab-1/ GM-Tg-hg-IP1119-Ab-2; GM-Tg-rg-IP1119-Ab-1/ GM-Tg-rg-IP1119-Ab-2;
GM-Tg-mg-IP1119-Ab-1/ GM-Tg-mg-IP1119-Ab-2; GM-Tg-cynog-IP1119-Ab-1/ GM-Tg-cynog-IP1119-Ab-2;
GM-Tg-felg-IP1119-Ab-1/ GM-Tg-felg-IP1119-Ab-2; GM-Tg-cang-IP1119-Ab-1/ GM-Tg-cang-IP1119-Ab-2;
GM-Tg-bovg-IP1119-Ab-1/ GM-Tg-bovg-IP1119-Ab-2; GM-Tg-equg-IP1119-Ab-1/ GM-Tg-equg-IP1119-Ab-2
Products NameAnti-LRRC52 monoclonal antibody
Formatmab
Target NameLRRC52
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-LRRC52 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1119-Ag-1Recombinant multi-species LRC52/ LRRC52 protein


    Target information

    Target IDGM-IP1119
    Target NameLRRC52
    Gene ID440699,240899,289199,696905,488671,101081020,536513,100060443
    Gene Symbol and Synonyms4930413P14Rik,LRRC52,RGD1312014
    Uniprot AccessionQ8N7C0
    Uniprot Entry NameLRC52_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162763
    Target ClassificationN/A

    The target: LRRC52, gene name: LRRC52, also named as . Enables potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Involved in positive regulation of voltage-gated potassium channel activity and potassium ion transmembrane transport. Part of voltage-gated potassium channel complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.