Anti-MAN2A2 monoclonal antibody

Pre-made anti-MAN2A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MAN2A2/MAN2A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1144-Ab-1/ GM-Tg-hg-IP1144-Ab-2Anti-Human MAN2A2 monoclonal antibodyHuman
GM-Tg-rg-IP1144-Ab-1/ GM-Tg-rg-IP1144-Ab-2Anti-Rat MAN2A2 monoclonal antibodyRat
GM-Tg-mg-IP1144-Ab-1/ GM-Tg-mg-IP1144-Ab-2Anti-Mouse MAN2A2 monoclonal antibodyMouse
GM-Tg-cynog-IP1144-Ab-1/ GM-Tg-cynog-IP1144-Ab-2Anti-Cynomolgus/ Rhesus macaque MAN2A2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1144-Ab-1/ GM-Tg-felg-IP1144-Ab-2Anti-Feline MAN2A2 monoclonal antibodyFeline
GM-Tg-cang-IP1144-Ab-1/ GM-Tg-cang-IP1144-Ab-2Anti-Canine MAN2A2 monoclonal antibodyCanine
GM-Tg-bovg-IP1144-Ab-1/ GM-Tg-bovg-IP1144-Ab-2Anti-Bovine MAN2A2 monoclonal antibodyBovine
GM-Tg-equg-IP1144-Ab-1/ GM-Tg-equg-IP1144-Ab-2Anti-Equine MAN2A2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1144-Ab-1/ GM-Tg-hg-IP1144-Ab-2; GM-Tg-rg-IP1144-Ab-1/ GM-Tg-rg-IP1144-Ab-2;
GM-Tg-mg-IP1144-Ab-1/ GM-Tg-mg-IP1144-Ab-2; GM-Tg-cynog-IP1144-Ab-1/ GM-Tg-cynog-IP1144-Ab-2;
GM-Tg-felg-IP1144-Ab-1/ GM-Tg-felg-IP1144-Ab-2; GM-Tg-cang-IP1144-Ab-1/ GM-Tg-cang-IP1144-Ab-2;
GM-Tg-bovg-IP1144-Ab-1/ GM-Tg-bovg-IP1144-Ab-2; GM-Tg-equg-IP1144-Ab-1/ GM-Tg-equg-IP1144-Ab-2
Products NameAnti-MAN2A2 monoclonal antibody
Formatmab
Target NameMAN2A2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MAN2A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1144-Ag-1Recombinant multi-species MA2A2/ MAN2A2/ MANA2X protein


    Target information

    Target IDGM-IP1144
    Target NameMAN2A2
    Gene ID4122,140481,308757,715720,488745,101101317,527449,100053432
    Gene Symbol and Synonyms1700052O22Rik,4931438M07Rik,Man IIx,MAN2A2,MANA2X,MX
    Uniprot AccessionP49641
    Uniprot Entry NameMA2A2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196547
    Target ClassificationN/A

    The target: MAN2A2, gene name: MAN2A2, also named as MANA2X. Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing and protein deglycosylation. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.