Anti-MARS monoclonal antibody

Pre-made anti-MARS monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MARS/MARS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1151-Ab-1/ GM-Tg-hg-IP1151-Ab-2Anti-Human MARS monoclonal antibodyHuman
GM-Tg-rg-IP1151-Ab-1/ GM-Tg-rg-IP1151-Ab-2Anti-Rat MARS monoclonal antibodyRat
GM-Tg-mg-IP1151-Ab-1/ GM-Tg-mg-IP1151-Ab-2Anti-Mouse MARS monoclonal antibodyMouse
GM-Tg-cynog-IP1151-Ab-1/ GM-Tg-cynog-IP1151-Ab-2Anti-Cynomolgus/ Rhesus macaque MARS monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1151-Ab-1/ GM-Tg-felg-IP1151-Ab-2Anti-Feline MARS monoclonal antibodyFeline
GM-Tg-cang-IP1151-Ab-1/ GM-Tg-cang-IP1151-Ab-2Anti-Canine MARS monoclonal antibodyCanine
GM-Tg-bovg-IP1151-Ab-1/ GM-Tg-bovg-IP1151-Ab-2Anti-Bovine MARS monoclonal antibodyBovine
GM-Tg-equg-IP1151-Ab-1/ GM-Tg-equg-IP1151-Ab-2Anti-Equine MARS monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1151-Ab-1/ GM-Tg-hg-IP1151-Ab-2; GM-Tg-rg-IP1151-Ab-1/ GM-Tg-rg-IP1151-Ab-2;
GM-Tg-mg-IP1151-Ab-1/ GM-Tg-mg-IP1151-Ab-2; GM-Tg-cynog-IP1151-Ab-1/ GM-Tg-cynog-IP1151-Ab-2;
GM-Tg-felg-IP1151-Ab-1/ GM-Tg-felg-IP1151-Ab-2; GM-Tg-cang-IP1151-Ab-1/ GM-Tg-cang-IP1151-Ab-2;
GM-Tg-bovg-IP1151-Ab-1/ GM-Tg-bovg-IP1151-Ab-2; GM-Tg-equg-IP1151-Ab-1/ GM-Tg-equg-IP1151-Ab-2
Products NameAnti-MARS monoclonal antibody
Formatmab
Target NameMARS
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MARS monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1151-Ag-1Recombinant multi-species SYMC/ MARS/ CMT2U protein


    Target information

    Target IDGM-IP1151
    Target NameMARS
    Gene ID4141,216443,299851,714744,474414,101093699,512531,100053373
    Gene Symbol and SynonymsCMT2U,ILFS2,ILLD,MARS,MARS1,METRS,MRS,MTRNS,SPG70,TTD9
    Uniprot AccessionP56192,Q2T9L8
    Uniprot Entry NameSYMC_HUMAN,SYMC_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000166986
    Target ClassificationTumor-associated antigen (TAA)

    The target: MARS, gene name: MARS, also named as CMT2U, ILFS2, ILLD, METRS, MRS, MTRNS, SPG70. This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.