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Anti-MBTPS2 monoclonal antibody
Pre-made anti-MBTPS2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MBTPS2/MBTPS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1157-Ab-1/ GM-Tg-hg-IP1157-Ab-2 | Anti-Human MBTPS2 monoclonal antibody | Human |
| GM-Tg-rg-IP1157-Ab-1/ GM-Tg-rg-IP1157-Ab-2 | Anti-Rat MBTPS2 monoclonal antibody | Rat |
| GM-Tg-mg-IP1157-Ab-1/ GM-Tg-mg-IP1157-Ab-2 | Anti-Mouse MBTPS2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1157-Ab-1/ GM-Tg-cynog-IP1157-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MBTPS2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1157-Ab-1/ GM-Tg-felg-IP1157-Ab-2 | Anti-Feline MBTPS2 monoclonal antibody | Feline |
| GM-Tg-cang-IP1157-Ab-1/ GM-Tg-cang-IP1157-Ab-2 | Anti-Canine MBTPS2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1157-Ab-1/ GM-Tg-bovg-IP1157-Ab-2 | Anti-Bovine MBTPS2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1157-Ab-1/ GM-Tg-equg-IP1157-Ab-2 | Anti-Equine MBTPS2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1157-Ab-1/ GM-Tg-hg-IP1157-Ab-2; GM-Tg-rg-IP1157-Ab-1/ GM-Tg-rg-IP1157-Ab-2; GM-Tg-mg-IP1157-Ab-1/ GM-Tg-mg-IP1157-Ab-2; GM-Tg-cynog-IP1157-Ab-1/ GM-Tg-cynog-IP1157-Ab-2; GM-Tg-felg-IP1157-Ab-1/ GM-Tg-felg-IP1157-Ab-2; GM-Tg-cang-IP1157-Ab-1/ GM-Tg-cang-IP1157-Ab-2; GM-Tg-bovg-IP1157-Ab-1/ GM-Tg-bovg-IP1157-Ab-2; GM-Tg-equg-IP1157-Ab-1/ GM-Tg-equg-IP1157-Ab-2 |
| Products Name | Anti-MBTPS2 monoclonal antibody |
| Format | mab |
| Target Name | MBTPS2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MBTPS2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1157-Ag-1 | Recombinant multi-species MBTP2/ MBTPS2/ BRESEK protein |
| ORF Viral Vector | pGMLP001067 | human MBTPS2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001067 | human MBTPS2 Lentivirus particle |
| ORF Viral Vector | pGMLPm003087 | mouse Mbtps2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003087 | mouse Mbtps2 Lentivirus particle |
Target information
| Target ID | GM-IP1157 |
| Target Name | MBTPS2 |
| Gene ID | 51360,270669,302705,696540,119868395,101084262,533134,100051796 |
| Gene Symbol and Synonyms | 9630032G22Rik,BRESEK,IFAP,KFSD,KFSDX,LRRGT00063,MBTPS2,OI19,OLMSX,S2P |
| Uniprot Accession | O43462,Q0III2 |
| Uniprot Entry Name | MBTP2_HUMAN,MBTP2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000012174 |
| Target Classification | N/A |
The target: MBTPS2, gene name: MBTPS2, also named as BRESEK, IFAP, KFSD, KFSDX, OI19, OLMSX, S2P. This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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