Anti-MCUR1 monoclonal antibody

Pre-made anti-MCUR1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MCUR1/MCUR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1161-Ab-1/ GM-Tg-hg-IP1161-Ab-2Anti-Human MCUR1 monoclonal antibodyHuman
GM-Tg-rg-IP1161-Ab-1/ GM-Tg-rg-IP1161-Ab-2Anti-Rat MCUR1 monoclonal antibodyRat
GM-Tg-mg-IP1161-Ab-1/ GM-Tg-mg-IP1161-Ab-2Anti-Mouse MCUR1 monoclonal antibodyMouse
GM-Tg-cynog-IP1161-Ab-1/ GM-Tg-cynog-IP1161-Ab-2Anti-Cynomolgus/ Rhesus macaque MCUR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1161-Ab-1/ GM-Tg-felg-IP1161-Ab-2Anti-Feline MCUR1 monoclonal antibodyFeline
GM-Tg-cang-IP1161-Ab-1/ GM-Tg-cang-IP1161-Ab-2Anti-Canine MCUR1 monoclonal antibodyCanine
GM-Tg-bovg-IP1161-Ab-1/ GM-Tg-bovg-IP1161-Ab-2Anti-Bovine MCUR1 monoclonal antibodyBovine
GM-Tg-equg-IP1161-Ab-1/ GM-Tg-equg-IP1161-Ab-2Anti-Equine MCUR1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1161-Ab-1/ GM-Tg-hg-IP1161-Ab-2; GM-Tg-rg-IP1161-Ab-1/ GM-Tg-rg-IP1161-Ab-2;
GM-Tg-mg-IP1161-Ab-1/ GM-Tg-mg-IP1161-Ab-2; GM-Tg-cynog-IP1161-Ab-1/ GM-Tg-cynog-IP1161-Ab-2;
GM-Tg-felg-IP1161-Ab-1/ GM-Tg-felg-IP1161-Ab-2; GM-Tg-cang-IP1161-Ab-1/ GM-Tg-cang-IP1161-Ab-2;
GM-Tg-bovg-IP1161-Ab-1/ GM-Tg-bovg-IP1161-Ab-2; GM-Tg-equg-IP1161-Ab-1/ GM-Tg-equg-IP1161-Ab-2
Products NameAnti-MCUR1 monoclonal antibody
Formatmab
Target NameMCUR1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MCUR1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1161-Ag-1Recombinant multi-species MCUR1/ C6orf79/ CCDC90A protein
    ORF Viral VectorpGMLPm005441mouse Mcur1 Lentivirus plasmid
    ORF Viral VectorvGMLPm005441mouse Mcur1 Lentivirus particle


    Target information

    Target IDGM-IP1161
    Target NameMCUR1
    Gene ID63933,76137,291034,701463,610095,101092181,617129,100065066
    Gene Symbol and Synonyms6230416A05Rik,C6orf79,CCDC90A,FMP32,MCUR1,RGD1307673
    Uniprot AccessionQ96AQ8
    Uniprot Entry NameMCUR1_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000050393
    Target ClassificationN/A

    The target: MCUR1, gene name: MCUR1, also named as C6orf79, CCDC90A, FMP32. Involved in calcium import into the mitochondrion and positive regulation of mitochondrial calcium ion concentration. Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.