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Anti-MED23 monoclonal antibody
Pre-made anti-MED23 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to MED23/MED23 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1162-Ab-1/ GM-Tg-hg-IP1162-Ab-2 | Anti-Human MED23 monoclonal antibody | Human |
| GM-Tg-rg-IP1162-Ab-1/ GM-Tg-rg-IP1162-Ab-2 | Anti-Rat MED23 monoclonal antibody | Rat |
| GM-Tg-mg-IP1162-Ab-1/ GM-Tg-mg-IP1162-Ab-2 | Anti-Mouse MED23 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1162-Ab-1/ GM-Tg-cynog-IP1162-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MED23 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1162-Ab-1/ GM-Tg-felg-IP1162-Ab-2 | Anti-Feline MED23 monoclonal antibody | Feline |
| GM-Tg-cang-IP1162-Ab-1/ GM-Tg-cang-IP1162-Ab-2 | Anti-Canine MED23 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1162-Ab-1/ GM-Tg-bovg-IP1162-Ab-2 | Anti-Bovine MED23 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1162-Ab-1/ GM-Tg-equg-IP1162-Ab-2 | Anti-Equine MED23 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1162-Ab-1/ GM-Tg-hg-IP1162-Ab-2; GM-Tg-rg-IP1162-Ab-1/ GM-Tg-rg-IP1162-Ab-2; GM-Tg-mg-IP1162-Ab-1/ GM-Tg-mg-IP1162-Ab-2; GM-Tg-cynog-IP1162-Ab-1/ GM-Tg-cynog-IP1162-Ab-2; GM-Tg-felg-IP1162-Ab-1/ GM-Tg-felg-IP1162-Ab-2; GM-Tg-cang-IP1162-Ab-1/ GM-Tg-cang-IP1162-Ab-2; GM-Tg-bovg-IP1162-Ab-1/ GM-Tg-bovg-IP1162-Ab-2; GM-Tg-equg-IP1162-Ab-1/ GM-Tg-equg-IP1162-Ab-2 |
| Products Name | Anti-MED23 monoclonal antibody |
| Format | mab |
| Target Name | MED23 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-MED23 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1162-Ag-1 | Recombinant multi-species MED23/ ARC130/ CRSP130 protein |
| ORF Viral Vector | pGMAD000512 | human MED23 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000512 | human MED23 Adenovirus particle |
Target information
| Target ID | GM-IP1162 |
| Target Name | MED23 |
| Gene ID | 9439,70208,309565,714629,474822,101093861,513610,100067556 |
| Gene Symbol and Synonyms | 130kDa,3000002A17Rik,ARC130,CRSP130,CRSP133,CRSP3,DRIP130,ES™7,MED23,mKIAA1216,MRT18,sno,snouty,SUR-2,SUR2 |
| Uniprot Accession | Q9ULK4,Q5EB59 |
| Uniprot Entry Name | MED23_HUMAN,MED23_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112282 |
| Target Classification | N/A |
The target: MED23, gene name: MED23, also named as ARC130, CRSP130, CRSP133, CRSP3, DRIP130, MRT18, SUR-2, SUR2. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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