Anti-METTL2B monoclonal antibody

Pre-made anti-METTL2B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to METTL2B/METTL2B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1169-Ab-1/ GM-Tg-hg-IP1169-Ab-2Anti-Human METTL2B monoclonal antibodyHuman
GM-Tg-rg-IP1169-Ab-1/ GM-Tg-rg-IP1169-Ab-2Anti-Rat METTL2B monoclonal antibodyRat
GM-Tg-mg-IP1169-Ab-1/ GM-Tg-mg-IP1169-Ab-2Anti-Mouse METTL2B monoclonal antibodyMouse
GM-Tg-cynog-IP1169-Ab-1/ GM-Tg-cynog-IP1169-Ab-2Anti-Cynomolgus/ Rhesus macaque METTL2B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1169-Ab-1/ GM-Tg-felg-IP1169-Ab-2Anti-Feline METTL2B monoclonal antibodyFeline
GM-Tg-cang-IP1169-Ab-1/ GM-Tg-cang-IP1169-Ab-2Anti-Canine METTL2B monoclonal antibodyCanine
GM-Tg-bovg-IP1169-Ab-1/ GM-Tg-bovg-IP1169-Ab-2Anti-Bovine METTL2B monoclonal antibodyBovine
GM-Tg-equg-IP1169-Ab-1/ GM-Tg-equg-IP1169-Ab-2Anti-Equine METTL2B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1169-Ab-1/ GM-Tg-hg-IP1169-Ab-2; GM-Tg-rg-IP1169-Ab-1/ GM-Tg-rg-IP1169-Ab-2;
GM-Tg-mg-IP1169-Ab-1/ GM-Tg-mg-IP1169-Ab-2; GM-Tg-cynog-IP1169-Ab-1/ GM-Tg-cynog-IP1169-Ab-2;
GM-Tg-felg-IP1169-Ab-1/ GM-Tg-felg-IP1169-Ab-2; GM-Tg-cang-IP1169-Ab-1/ GM-Tg-cang-IP1169-Ab-2;
GM-Tg-bovg-IP1169-Ab-1/ GM-Tg-bovg-IP1169-Ab-2; GM-Tg-equg-IP1169-Ab-1/ GM-Tg-equg-IP1169-Ab-2
Products NameAnti-METTL2B monoclonal antibody
Formatmab
Target NameMETTL2B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-METTL2B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1169-Ag-1Recombinant multi-species MET2B/ METTL2B/ METL protein


    Target information

    Target IDGM-IP1169
    Target NameMETTL2B
    Gene ID55798
    Gene Symbol and SynonymsMETL,METTL2,METTL2A,METTL2B,PSENIP1
    Uniprot AccessionQ6P1Q9
    Uniprot Entry NameMET2B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165055
    Target ClassificationN/A

    The target: METTL2B, gene name: METTL2B, also named as METL, METTL2, METTL2A, PSENIP1. This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.