Anti-MFSD12 monoclonal antibody

Pre-made anti-MFSD12 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MFSD12/MFSD12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1178-Ab-1/ GM-Tg-hg-IP1178-Ab-2Anti-Human MFSD12 monoclonal antibodyHuman
GM-Tg-rg-IP1178-Ab-1/ GM-Tg-rg-IP1178-Ab-2Anti-Rat MFSD12 monoclonal antibodyRat
GM-Tg-mg-IP1178-Ab-1/ GM-Tg-mg-IP1178-Ab-2Anti-Mouse MFSD12 monoclonal antibodyMouse
GM-Tg-cynog-IP1178-Ab-1/ GM-Tg-cynog-IP1178-Ab-2Anti-Cynomolgus/ Rhesus macaque MFSD12 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1178-Ab-1/ GM-Tg-felg-IP1178-Ab-2Anti-Feline MFSD12 monoclonal antibodyFeline
GM-Tg-cang-IP1178-Ab-1/ GM-Tg-cang-IP1178-Ab-2Anti-Canine MFSD12 monoclonal antibodyCanine
GM-Tg-bovg-IP1178-Ab-1/ GM-Tg-bovg-IP1178-Ab-2Anti-Bovine MFSD12 monoclonal antibodyBovine
GM-Tg-equg-IP1178-Ab-1/ GM-Tg-equg-IP1178-Ab-2Anti-Equine MFSD12 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1178-Ab-1/ GM-Tg-hg-IP1178-Ab-2; GM-Tg-rg-IP1178-Ab-1/ GM-Tg-rg-IP1178-Ab-2;
GM-Tg-mg-IP1178-Ab-1/ GM-Tg-mg-IP1178-Ab-2; GM-Tg-cynog-IP1178-Ab-1/ GM-Tg-cynog-IP1178-Ab-2;
GM-Tg-felg-IP1178-Ab-1/ GM-Tg-felg-IP1178-Ab-2; GM-Tg-cang-IP1178-Ab-1/ GM-Tg-cang-IP1178-Ab-2;
GM-Tg-bovg-IP1178-Ab-1/ GM-Tg-bovg-IP1178-Ab-2; GM-Tg-equg-IP1178-Ab-1/ GM-Tg-equg-IP1178-Ab-2
Products NameAnti-MFSD12 monoclonal antibody
Formatmab
Target NameMFSD12
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MFSD12 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1178-Ag-1Recombinant multi-species MFS12/ MFSD12/ C19orf28 protein


    Target information

    Target IDGM-IP1178
    Target NameMFSD12
    Gene ID126321,73822,362824,713171,485058,101088306,112447369,111774443
    Gene Symbol and SynonymsC19orf28,C20H19orf28,C7H19orf28,F630110N24Rik,gr,MFSD12,PP3501,RGD1307722,Wdt1
    Uniprot AccessionQ6NUT3,F1PZV2
    Uniprot Entry NameMFS12_HUMAN,MFS12_CANLF
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000161091
    Target ClassificationN/A

    The target: MFSD12, gene name: MFSD12, also named as C19orf28, PP3501. Enables cysteine transmembrane transporter activity. Involved in cysteine transmembrane transport; pigment metabolic process involved in pigmentation; and regulation of melanin biosynthetic process. Located in lysosome and melanosome. Part of late endosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.