Anti-MIEF2 monoclonal antibody

Pre-made anti-MIEF2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MIEF2/MIEF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1192-Ab-1/ GM-Tg-hg-IP1192-Ab-2Anti-Human MIEF2 monoclonal antibodyHuman
GM-Tg-rg-IP1192-Ab-1/ GM-Tg-rg-IP1192-Ab-2Anti-Rat MIEF2 monoclonal antibodyRat
GM-Tg-mg-IP1192-Ab-1/ GM-Tg-mg-IP1192-Ab-2Anti-Mouse MIEF2 monoclonal antibodyMouse
GM-Tg-cynog-IP1192-Ab-1/ GM-Tg-cynog-IP1192-Ab-2Anti-Cynomolgus/ Rhesus macaque MIEF2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1192-Ab-1/ GM-Tg-felg-IP1192-Ab-2Anti-Feline MIEF2 monoclonal antibodyFeline
GM-Tg-cang-IP1192-Ab-1/ GM-Tg-cang-IP1192-Ab-2Anti-Canine MIEF2 monoclonal antibodyCanine
GM-Tg-bovg-IP1192-Ab-1/ GM-Tg-bovg-IP1192-Ab-2Anti-Bovine MIEF2 monoclonal antibodyBovine
GM-Tg-equg-IP1192-Ab-1/ GM-Tg-equg-IP1192-Ab-2Anti-Equine MIEF2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1192-Ab-1/ GM-Tg-hg-IP1192-Ab-2; GM-Tg-rg-IP1192-Ab-1/ GM-Tg-rg-IP1192-Ab-2;
GM-Tg-mg-IP1192-Ab-1/ GM-Tg-mg-IP1192-Ab-2; GM-Tg-cynog-IP1192-Ab-1/ GM-Tg-cynog-IP1192-Ab-2;
GM-Tg-felg-IP1192-Ab-1/ GM-Tg-felg-IP1192-Ab-2; GM-Tg-cang-IP1192-Ab-1/ GM-Tg-cang-IP1192-Ab-2;
GM-Tg-bovg-IP1192-Ab-1/ GM-Tg-bovg-IP1192-Ab-2; GM-Tg-equg-IP1192-Ab-1/ GM-Tg-equg-IP1192-Ab-2
Products NameAnti-MIEF2 monoclonal antibody
Formatmab
Target NameMIEF2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MIEF2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1192-Ag-1Recombinant multi-species MID49/ MIEF2/ SMCR7 protein


    Target information

    Target IDGM-IP1192
    Target NameMIEF2
    Gene ID125170,237781,497916,700705,101099599,515229,100050635
    Gene Symbol and SynonymsCOXPD49,Gm11,MID49,MIEF2,RGD1560728,SMCR7
    Uniprot AccessionQ96C03
    Uniprot Entry NameMID49_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000177427
    Target ClassificationN/A

    The target: MIEF2, gene name: MIEF2, also named as MID49, SMCR7. This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.