Anti-MRRF monoclonal antibody

Pre-made anti-MRRF monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MRRF/MRRF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1211-Ab-1/ GM-Tg-hg-IP1211-Ab-2Anti-Human MRRF monoclonal antibodyHuman
GM-Tg-rg-IP1211-Ab-1/ GM-Tg-rg-IP1211-Ab-2Anti-Rat MRRF monoclonal antibodyRat
GM-Tg-mg-IP1211-Ab-1/ GM-Tg-mg-IP1211-Ab-2Anti-Mouse MRRF monoclonal antibodyMouse
GM-Tg-cynog-IP1211-Ab-1/ GM-Tg-cynog-IP1211-Ab-2Anti-Cynomolgus/ Rhesus macaque MRRF monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1211-Ab-1/ GM-Tg-felg-IP1211-Ab-2Anti-Feline MRRF monoclonal antibodyFeline
GM-Tg-cang-IP1211-Ab-1/ GM-Tg-cang-IP1211-Ab-2Anti-Canine MRRF monoclonal antibodyCanine
GM-Tg-bovg-IP1211-Ab-1/ GM-Tg-bovg-IP1211-Ab-2Anti-Bovine MRRF monoclonal antibodyBovine
GM-Tg-equg-IP1211-Ab-1/ GM-Tg-equg-IP1211-Ab-2Anti-Equine MRRF monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1211-Ab-1/ GM-Tg-hg-IP1211-Ab-2; GM-Tg-rg-IP1211-Ab-1/ GM-Tg-rg-IP1211-Ab-2;
GM-Tg-mg-IP1211-Ab-1/ GM-Tg-mg-IP1211-Ab-2; GM-Tg-cynog-IP1211-Ab-1/ GM-Tg-cynog-IP1211-Ab-2;
GM-Tg-felg-IP1211-Ab-1/ GM-Tg-felg-IP1211-Ab-2; GM-Tg-cang-IP1211-Ab-1/ GM-Tg-cang-IP1211-Ab-2;
GM-Tg-bovg-IP1211-Ab-1/ GM-Tg-bovg-IP1211-Ab-2; GM-Tg-equg-IP1211-Ab-1/ GM-Tg-equg-IP1211-Ab-2
Products NameAnti-MRRF monoclonal antibody
Formatmab
Target NameMRRF
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MRRF monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1211-Ag-1Recombinant multi-species RRFM/ MRRF/ MRFF protein


    Target information

    Target IDGM-IP1211
    Target NameMRRF
    Gene ID92399,67871,311903,700902,480739,101092304,614013,100071623
    Gene Symbol and Synonyms2400002D02Rik,MRFF,MRRF,MTRRF,RRF
    Uniprot AccessionQ96E11,Q5RKI9,Q0VCQ4
    Uniprot Entry NameRRFM_HUMAN,RRFM_RAT,RRFM_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000148187
    Target ClassificationN/A

    The target: MRRF, gene name: MRRF, also named as MRFF, MTRRF, RRF. This gene encodes a ribosome recycling factor, which is a component of the mitochondrial translational machinery. The encoded protein, along with mitochondrial elongation factor 2, functions in ribosomal recycling at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Oct 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.