Anti-MYRF monoclonal antibody

Pre-made anti-MYRF monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MYRF/MYRF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1229-Ab-1/ GM-Tg-hg-IP1229-Ab-2Anti-Human MYRF monoclonal antibodyHuman
GM-Tg-rg-IP1229-Ab-1/ GM-Tg-rg-IP1229-Ab-2Anti-Rat MYRF monoclonal antibodyRat
GM-Tg-mg-IP1229-Ab-1/ GM-Tg-mg-IP1229-Ab-2Anti-Mouse MYRF monoclonal antibodyMouse
GM-Tg-cynog-IP1229-Ab-1/ GM-Tg-cynog-IP1229-Ab-2Anti-Cynomolgus/ Rhesus macaque MYRF monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1229-Ab-1/ GM-Tg-felg-IP1229-Ab-2Anti-Feline MYRF monoclonal antibodyFeline
GM-Tg-cang-IP1229-Ab-1/ GM-Tg-cang-IP1229-Ab-2Anti-Canine MYRF monoclonal antibodyCanine
GM-Tg-bovg-IP1229-Ab-1/ GM-Tg-bovg-IP1229-Ab-2Anti-Bovine MYRF monoclonal antibodyBovine
GM-Tg-equg-IP1229-Ab-1/ GM-Tg-equg-IP1229-Ab-2Anti-Equine MYRF monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1229-Ab-1/ GM-Tg-hg-IP1229-Ab-2; GM-Tg-rg-IP1229-Ab-1/ GM-Tg-rg-IP1229-Ab-2;
GM-Tg-mg-IP1229-Ab-1/ GM-Tg-mg-IP1229-Ab-2; GM-Tg-cynog-IP1229-Ab-1/ GM-Tg-cynog-IP1229-Ab-2;
GM-Tg-felg-IP1229-Ab-1/ GM-Tg-felg-IP1229-Ab-2; GM-Tg-cang-IP1229-Ab-1/ GM-Tg-cang-IP1229-Ab-2;
GM-Tg-bovg-IP1229-Ab-1/ GM-Tg-bovg-IP1229-Ab-2; GM-Tg-equg-IP1229-Ab-1/ GM-Tg-equg-IP1229-Ab-2
Products NameAnti-MYRF monoclonal antibody
Formatmab
Target NameMYRF
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MYRF monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1229-Ag-1Recombinant multi-species MYRF/ 11orf9/ C11orf9 protein


    Target information

    Target IDGM-IP1229
    Target NameMYRF
    Gene ID745,225908,293736,719083,483794,101083206,509704,100059805
    Gene Symbol and Synonyms11orf9,6030439E18,C11orf9,C14H11orf9,C18H11orf9,C29H11orf9,CD1H11orf9,CUGS,Gm1804,Gm98,MMERV,MRF,MYRF,Ndt80,pqn-47,RGD1306622
    Uniprot AccessionQ9Y2G1
    Uniprot Entry NameMYRF_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000124920
    Target ClassificationN/A

    The target: MYRF, gene name: MYRF, also named as 11orf9, C11orf9, MMERV, MRF, Ndt80, pqn-47. This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.