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Anti-NCKIPSD monoclonal antibody
Pre-made anti-NCKIPSD monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NCKIPSD/NCKIPSD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1241-Ab-1/ GM-Tg-hg-IP1241-Ab-2 | Anti-Human NCKIPSD monoclonal antibody | Human |
| GM-Tg-rg-IP1241-Ab-1/ GM-Tg-rg-IP1241-Ab-2 | Anti-Rat NCKIPSD monoclonal antibody | Rat |
| GM-Tg-mg-IP1241-Ab-1/ GM-Tg-mg-IP1241-Ab-2 | Anti-Mouse NCKIPSD monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1241-Ab-1/ GM-Tg-cynog-IP1241-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NCKIPSD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1241-Ab-1/ GM-Tg-felg-IP1241-Ab-2 | Anti-Feline NCKIPSD monoclonal antibody | Feline |
| GM-Tg-cang-IP1241-Ab-1/ GM-Tg-cang-IP1241-Ab-2 | Anti-Canine NCKIPSD monoclonal antibody | Canine |
| GM-Tg-bovg-IP1241-Ab-1/ GM-Tg-bovg-IP1241-Ab-2 | Anti-Bovine NCKIPSD monoclonal antibody | Bovine |
| GM-Tg-equg-IP1241-Ab-1/ GM-Tg-equg-IP1241-Ab-2 | Anti-Equine NCKIPSD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1241-Ab-1/ GM-Tg-hg-IP1241-Ab-2; GM-Tg-rg-IP1241-Ab-1/ GM-Tg-rg-IP1241-Ab-2; GM-Tg-mg-IP1241-Ab-1/ GM-Tg-mg-IP1241-Ab-2; GM-Tg-cynog-IP1241-Ab-1/ GM-Tg-cynog-IP1241-Ab-2; GM-Tg-felg-IP1241-Ab-1/ GM-Tg-felg-IP1241-Ab-2; GM-Tg-cang-IP1241-Ab-1/ GM-Tg-cang-IP1241-Ab-2; GM-Tg-bovg-IP1241-Ab-1/ GM-Tg-bovg-IP1241-Ab-2; GM-Tg-equg-IP1241-Ab-1/ GM-Tg-equg-IP1241-Ab-2 |
| Products Name | Anti-NCKIPSD monoclonal antibody |
| Format | mab |
| Target Name | NCKIPSD |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NCKIPSD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1241-Ag-1 | Recombinant multi-species SPN90/ NCKIPSD/ AF3P21 protein |
Target information
| Target ID | GM-IP1241 |
| Target Name | NCKIPSD |
| Gene ID | 51517,80987,301009,709410,484776,101099944,516941,100146927 |
| Gene Symbol and Synonyms | AF3P21,DIP,DIP1,NCKIPSD,ORF1,SPIN90,VIP54,Wasbp,WASLBP,WISH |
| Uniprot Accession | Q9NZQ3 |
| Uniprot Entry Name | SPN90_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000213672 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: NCKIPSD, gene name: NCKIPSD, also named as AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH. The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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