Anti-NCMAP monoclonal antibody

Pre-made anti-NCMAP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to NCMAP/NCMAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1243-Ab-1/ GM-Tg-hg-IP1243-Ab-2Anti-Human NCMAP monoclonal antibodyHuman
GM-Tg-rg-IP1243-Ab-1/ GM-Tg-rg-IP1243-Ab-2Anti-Rat NCMAP monoclonal antibodyRat
GM-Tg-mg-IP1243-Ab-1/ GM-Tg-mg-IP1243-Ab-2Anti-Mouse NCMAP monoclonal antibodyMouse
GM-Tg-cynog-IP1243-Ab-1/ GM-Tg-cynog-IP1243-Ab-2Anti-Cynomolgus/ Rhesus macaque NCMAP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1243-Ab-1/ GM-Tg-felg-IP1243-Ab-2Anti-Feline NCMAP monoclonal antibodyFeline
GM-Tg-cang-IP1243-Ab-1/ GM-Tg-cang-IP1243-Ab-2Anti-Canine NCMAP monoclonal antibodyCanine
GM-Tg-bovg-IP1243-Ab-1/ GM-Tg-bovg-IP1243-Ab-2Anti-Bovine NCMAP monoclonal antibodyBovine
GM-Tg-equg-IP1243-Ab-1/ GM-Tg-equg-IP1243-Ab-2Anti-Equine NCMAP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1243-Ab-1/ GM-Tg-hg-IP1243-Ab-2; GM-Tg-rg-IP1243-Ab-1/ GM-Tg-rg-IP1243-Ab-2;
GM-Tg-mg-IP1243-Ab-1/ GM-Tg-mg-IP1243-Ab-2; GM-Tg-cynog-IP1243-Ab-1/ GM-Tg-cynog-IP1243-Ab-2;
GM-Tg-felg-IP1243-Ab-1/ GM-Tg-felg-IP1243-Ab-2; GM-Tg-cang-IP1243-Ab-1/ GM-Tg-cang-IP1243-Ab-2;
GM-Tg-bovg-IP1243-Ab-1/ GM-Tg-bovg-IP1243-Ab-2; GM-Tg-equg-IP1243-Ab-1/ GM-Tg-equg-IP1243-Ab-2
Products NameAnti-NCMAP monoclonal antibody
Formatmab
Target NameNCMAP
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-NCMAP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1243-Ag-1Recombinant multi-species NCMAP/ C1orf130/ MP11 protein


    Target information

    Target IDGM-IP1243
    Target NameNCMAP
    Gene ID400746,230822,689826,712192,612254,101101650,614724,100057526
    Gene Symbol and SynonymsA330049M08Rik,C1H1orf130,C1orf130,C2H1orf130,MP11,NCMAP
    Uniprot AccessionQ5T1S8,F1M2Z5
    Uniprot Entry NameNCMAP_HUMAN,NCMAP_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184454
    Target ClassificationN/A

    The target: NCMAP, gene name: NCMAP, also named as C1orf130, MP11. Predicted to be a structural constituent of myelin sheath. Predicted to be involved in peripheral nervous system myelin formation and positive regulation of myelination. Predicted to be integral component of plasma membrane. Predicted to be active in Schmidt-Lanterman incisure and paranode region of axon. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.