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Anti-NDRG4 monoclonal antibody
Pre-made anti-NDRG4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NDRG4/NDRG4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1247-Ab-1/ GM-Tg-hg-IP1247-Ab-2 | Anti-Human NDRG4 monoclonal antibody | Human |
| GM-Tg-rg-IP1247-Ab-1/ GM-Tg-rg-IP1247-Ab-2 | Anti-Rat NDRG4 monoclonal antibody | Rat |
| GM-Tg-mg-IP1247-Ab-1/ GM-Tg-mg-IP1247-Ab-2 | Anti-Mouse NDRG4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1247-Ab-1/ GM-Tg-cynog-IP1247-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NDRG4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1247-Ab-1/ GM-Tg-felg-IP1247-Ab-2 | Anti-Feline NDRG4 monoclonal antibody | Feline |
| GM-Tg-cang-IP1247-Ab-1/ GM-Tg-cang-IP1247-Ab-2 | Anti-Canine NDRG4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1247-Ab-1/ GM-Tg-bovg-IP1247-Ab-2 | Anti-Bovine NDRG4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1247-Ab-1/ GM-Tg-equg-IP1247-Ab-2 | Anti-Equine NDRG4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1247-Ab-1/ GM-Tg-hg-IP1247-Ab-2; GM-Tg-rg-IP1247-Ab-1/ GM-Tg-rg-IP1247-Ab-2; GM-Tg-mg-IP1247-Ab-1/ GM-Tg-mg-IP1247-Ab-2; GM-Tg-cynog-IP1247-Ab-1/ GM-Tg-cynog-IP1247-Ab-2; GM-Tg-felg-IP1247-Ab-1/ GM-Tg-felg-IP1247-Ab-2; GM-Tg-cang-IP1247-Ab-1/ GM-Tg-cang-IP1247-Ab-2; GM-Tg-bovg-IP1247-Ab-1/ GM-Tg-bovg-IP1247-Ab-2; GM-Tg-equg-IP1247-Ab-1/ GM-Tg-equg-IP1247-Ab-2 |
| Products Name | Anti-NDRG4 monoclonal antibody |
| Format | mab |
| Target Name | NDRG4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NDRG4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1247-Ag-1 | Recombinant multi-species NDRG4/ BDM1/ SMAP-8 protein |
| ORF Viral Vector | pGMLP001971 | human NDRG4 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001971 | human NDRG4 Lentivirus particle |
| ORF Viral Vector | pGMLPm001653 | mouse Ndrg4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001653 | mouse Ndrg4 Lentivirus particle |
Target information
| Target ID | GM-IP1247 |
| Target Name | NDRG4 |
| Gene ID | 65009,234593,64457,712742,611099,101089229,515033,100052493 |
| Gene Symbol and Synonyms | BDM1,D8Bwg1337e,Ndr1-rs,Ndr4,NDRG4,SMAP-8,SMAP8 |
| Uniprot Accession | Q9ULP0,Q9Z2L9 |
| Uniprot Entry Name | NDRG4_HUMAN,NDRG4_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Colorectal Cancer |
| Gene Ensembl | ENSG00000103034 |
| Target Classification | N/A |
The target: NDRG4, gene name: NDRG4, also named as BDM1, SMAP-8, SMAP8. This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.[provided by RefSeq, Jun 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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