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Anti-NDUFB3 monoclonal antibody
Pre-made anti-NDUFB3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NDUFB3/NDUFB3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1259-Ab-1/ GM-Tg-hg-IP1259-Ab-2 | Anti-Human NDUFB3 monoclonal antibody | Human |
| GM-Tg-rg-IP1259-Ab-1/ GM-Tg-rg-IP1259-Ab-2 | Anti-Rat NDUFB3 monoclonal antibody | Rat |
| GM-Tg-mg-IP1259-Ab-1/ GM-Tg-mg-IP1259-Ab-2 | Anti-Mouse NDUFB3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1259-Ab-1/ GM-Tg-cynog-IP1259-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NDUFB3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1259-Ab-1/ GM-Tg-felg-IP1259-Ab-2 | Anti-Feline NDUFB3 monoclonal antibody | Feline |
| GM-Tg-cang-IP1259-Ab-1/ GM-Tg-cang-IP1259-Ab-2 | Anti-Canine NDUFB3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1259-Ab-1/ GM-Tg-bovg-IP1259-Ab-2 | Anti-Bovine NDUFB3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1259-Ab-1/ GM-Tg-equg-IP1259-Ab-2 | Anti-Equine NDUFB3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1259-Ab-1/ GM-Tg-hg-IP1259-Ab-2; GM-Tg-rg-IP1259-Ab-1/ GM-Tg-rg-IP1259-Ab-2; GM-Tg-mg-IP1259-Ab-1/ GM-Tg-mg-IP1259-Ab-2; GM-Tg-cynog-IP1259-Ab-1/ GM-Tg-cynog-IP1259-Ab-2; GM-Tg-felg-IP1259-Ab-1/ GM-Tg-felg-IP1259-Ab-2; GM-Tg-cang-IP1259-Ab-1/ GM-Tg-cang-IP1259-Ab-2; GM-Tg-bovg-IP1259-Ab-1/ GM-Tg-bovg-IP1259-Ab-2; GM-Tg-equg-IP1259-Ab-1/ GM-Tg-equg-IP1259-Ab-2 |
| Products Name | Anti-NDUFB3 monoclonal antibody |
| Format | mab |
| Target Name | NDUFB3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NDUFB3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1259-Ag-1 | Recombinant multi-species NDUB3/ NDUFB3/ B12 protein |
| ORF Viral Vector | pGMLP004252 | human NDUFB3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004252 | human NDUFB3 Lentivirus particle |
Target information
| Target ID | GM-IP1259 |
| Target Name | NDUFB3 |
| Gene ID | 4709,66495,301427,700944,100855975,101093382,338073,100067936 |
| Gene Symbol and Synonyms | 2700033I16Rik,B12,CI-B12,MC1DN25,NDUFB3 |
| Uniprot Accession | O43676,Q02365 |
| Uniprot Entry Name | NDUB3_HUMAN,NDUB3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000119013 |
| Target Classification | N/A |
The target: NDUFB3, gene name: NDUFB3, also named as B12, CI-B12. This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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