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Anti-NUP107 monoclonal antibody
Pre-made anti-NUP107 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NUP107/NUP107 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1286-Ab-1/ GM-Tg-hg-IP1286-Ab-2 | Anti-Human NUP107 monoclonal antibody | Human |
| GM-Tg-rg-IP1286-Ab-1/ GM-Tg-rg-IP1286-Ab-2 | Anti-Rat NUP107 monoclonal antibody | Rat |
| GM-Tg-mg-IP1286-Ab-1/ GM-Tg-mg-IP1286-Ab-2 | Anti-Mouse NUP107 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1286-Ab-1/ GM-Tg-cynog-IP1286-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NUP107 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1286-Ab-1/ GM-Tg-felg-IP1286-Ab-2 | Anti-Feline NUP107 monoclonal antibody | Feline |
| GM-Tg-cang-IP1286-Ab-1/ GM-Tg-cang-IP1286-Ab-2 | Anti-Canine NUP107 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1286-Ab-1/ GM-Tg-bovg-IP1286-Ab-2 | Anti-Bovine NUP107 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1286-Ab-1/ GM-Tg-equg-IP1286-Ab-2 | Anti-Equine NUP107 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1286-Ab-1/ GM-Tg-hg-IP1286-Ab-2; GM-Tg-rg-IP1286-Ab-1/ GM-Tg-rg-IP1286-Ab-2; GM-Tg-mg-IP1286-Ab-1/ GM-Tg-mg-IP1286-Ab-2; GM-Tg-cynog-IP1286-Ab-1/ GM-Tg-cynog-IP1286-Ab-2; GM-Tg-felg-IP1286-Ab-1/ GM-Tg-felg-IP1286-Ab-2; GM-Tg-cang-IP1286-Ab-1/ GM-Tg-cang-IP1286-Ab-2; GM-Tg-bovg-IP1286-Ab-1/ GM-Tg-bovg-IP1286-Ab-2; GM-Tg-equg-IP1286-Ab-1/ GM-Tg-equg-IP1286-Ab-2 |
| Products Name | Anti-NUP107 monoclonal antibody |
| Format | mab |
| Target Name | NUP107 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NUP107 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1286-Ag-1 | Recombinant multi-species NU107/ NUP107/ NPHS11 protein |
| ORF Viral Vector | vGMLP002786 | human NUP107 Lentivirus particle |
| ORF Viral Vector | pGMLP002786 | human NUP107 Lentivirus plasmid |
Target information
| Target ID | GM-IP1286 |
| Target Name | NUP107 |
| Gene ID | 57122,103468,116555,718214,474440,101096904,504823,100059287 |
| Gene Symbol and Synonyms | NPHS11,NUP107,NUP84,ODG6,ODG6; GAMOS7 |
| Uniprot Accession | P57740,P52590 |
| Uniprot Entry Name | NU107_HUMAN,NU107_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | IgA glomerulonephritis |
| Gene Ensembl | ENSG00000111581 |
| Target Classification | N/A |
The target: NUP107, gene name: NUP107, also named as NPHS11, NUP84, ODG6. This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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